| Identification | Back Directory | [Name]
20-O-Acetylingenol-3-angelate | [CAS]
82425-35-2 | [Synonyms]
PEP 008
Euphorbia factor Pe1
20-O-Acetylingenol-3-angelate
20-O-Acetylingenol-3-angelate 82425-35-2
20-O-Acetylingenol-3-angelate (Euphorbia factor Pe1)
2-Butenoic acid, 2-methyl-, (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-4-[(acetyloxy)methyl]-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester, (2Z)- | [Molecular Formula]
C27H36O7 | [MDL Number]
MFCD28978168 | [MOL File]
82425-35-2.mol | [Molecular Weight]
472.57 |
| Chemical Properties | Back Directory | [solubility ]
Acetonitrile: Slightly soluble: 0.1-1 mg/ml
Chloroform: Sparingly soluble: 1-10 mg/ml | [form ]
Solid | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
20-O-Acetylingenol-3-angelate is a molluscicidal agent present in extracts from Euphorbia conspicua N. E. Br. Anti-cancer agent. Cytostatic agent. | [References]
[1] SHARON A MASON. The induction of senescence-like growth arrest by protein kinase C-activating diterpene esters in solid tumor cells.[J]. Investigational New Drugs, 2010, 28 5: 575-586. DOI: 10.1007/s10637-009-9292-y
[2] MING LIU. Synthesis and Cytotoxicity against K562 Cells of 3-O-Angeloyl-20-O-acetyl Ingenol, a Derivative of Ingenol Mebutate.[J]. International Journal of Molecular Sciences, 2016, 17 8. DOI: 10.3390/ijms17081348 |
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