| Identification | Back Directory | [Name]
CUCURBITACIN IIA | [CAS]
58546-34-2 | [Synonyms]
Hemslecin A
CUCURBITACIN IIA
Dihydrocucurbitacin Q1
HEMSLECIN A; CUCURBITACIN IIA
Dihydrocucurbitacin F 25-O-acetate
25-Acetoxy-23,24-dihydrocucurbitacin F
25-O-Acetyl-23,24-dihydrocucurbitacin F
23,24-Dihydrocucurbitacin F-25-O-acetate | [Molecular Formula]
C32H50O8 | [MDL Number]
MFCD07781419 | [MOL File]
58546-34-2.mol | [Molecular Weight]
562.73 |
| Chemical Properties | Back Directory | [Boiling point ]
679.1±55.0 °C(Predicted) | [density ]
1.22 | [storage temp. ]
4°C, protect from light | [solubility ]
Soluble in methan | [form ]
powder | [pka]
12.81±0.29(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents. | [Uses]
Cucurbitacin IIa has the effect of inhibiting Shigella, Salmonella typhi and Salmonella choleraesuis. | [Biological Activity]
Cucurbitacin IIa is a triterpene isolated from orchard fruit snow gall, which can induce apoptosis in cancer cells. It reduces the expression of survivin, reduces the level of phosphorylated histone H3, and increases the level of cleaved PARP in cancer cells. | [storage]
4°C, protect from light |
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