| Identification | More | [Name]
DELAPRIL HCL | [CAS]
83435-67-0 | [Synonyms]
DELAPRIL HCL
delapril hydrochloride
Dalapril Hcl
N-(N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)-L-alanyl)-N-(indan-2-yl)gly cine hydrochloride
Adecut
Cupressin
CV 3317
Glycine, N-(2,3-dihydro-1H-inden-2-yl)-N-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-, monohydrochloride, (S)-
Glycine, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-N-(2,3-dihydro-1H-inden-2-yl)-, monohydrochloride
REV 6000A
Defolder | [Molecular Formula]
C26H32N2O5.HCl | [MDL Number]
MFCD00884619 | [MOL File]
83435-67-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
166-170℃ | [alpha ]
D22 +18.5° (c = 1 in methanol) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [solubility ]
DMSO:174.0(Max Conc. mg/mL);355.82(Max Conc. mM) | [form ]
Solid | [color ]
White to off-white | [InChIKey]
FDJCVHVKXFIEPJ-YSHIOSSBNA-N | [SMILES]
C1(CC2C=CC=CC=2C1)N(CC(=O)O)C(=O)[C@H](C)N[C@H](C(=O)OCC)CCC1=CC=CC=C1.Cl |&1:16,19,r| | [CAS DataBase Reference]
83435-67-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS06 | [Signal word ]
Danger | [Hazard statements ]
H301 | [Precautionary statements ]
P280-P305+P351+P338 | [RTECS ]
MB9668000 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral |
| Hazard Information | Back Directory | [Description]
Delapril is a new angiotensin-converting enzyme (ACE) inhibitor useful in the treatment
of essential hypertension. Orally administered delapril is a prodrug which is de-esterified
to its active diacid metabolite. In hypertensive patients delapril significantly decreased
systolic blood pressure and ACE activity 24 hours after dosing without affecting
endogeneous creatinine clearance. | [Originator]
Takeda (Japan) | [Uses]
Antihypertensive; enzyme inhibitor (angiotensinconverting). | [Uses]
Delapril Hydrochloride is an angiotensin-converting-enzyme inhibitor (ACE) used as an antihypertensive drug in some European and Asian countries, but not in America. | [Definition]
ChEBI: Delapril hydrochloride is a peptide. | [Brand name]
Adecut |
|
| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
| Company Name: |
TCI Europe
|
| Tel: |
320-37350700 |
| Website: |
https://www.tcichemicals.com/de/de/index.html |
|