| Identification | More | [Name]
2,5-Difluoropyridine | [CAS]
84476-99-3 | [Synonyms]
2,5-DIFLUOROPYRIDINE | [Molecular Formula]
C5H3F2N | [MDL Number]
MFCD04114191 | [Molecular Weight]
115.08 | [MOL File]
84476-99-3.mol |
| Chemical Properties | Back Directory | [Melting point ]
-33°C(lit.) | [Boiling point ]
115°C(lit.) | [density ]
1.274 g/mL at 25 °C | [Fp ]
24℃ | [refractive index ]
1.4440 | [storage temp. ]
Inert atmosphere,2-8°C | [form ]
clear liquid | [pka]
-2.85±0.10(Predicted) | [color ]
Colorless to Light yellow | [InChI]
InChI=1S/C5H3F2N/c6-4-1-2-5(7)8-3-4/h1-3H | [InChIKey]
XFAMUOYNXFXQTC-UHFFFAOYSA-N | [SMILES]
C1(F)=NC=C(F)C=C1 | [CAS DataBase Reference]
84476-99-3(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Uses]
2,5-Difluoropyridine is a pyridine derivative, mainly used as a pharmaceutical intermediate. | [Application]
2,5-Difluoropyridine is a starting material for the synthesis of many drugs, and an important intermediate for many pyridine compounds. For example, 2,5-Difluoropyridine can be used to synthesize 8-chloro-1-cyclopropyl-7-fluoro-9-methyl-4-oxo-4-hydro-quinazine-3-carboxylate, which is an important intermediate for a class of antibacterial drugs. |
| Safety Data | Back Directory | [Hazard Codes ]
T,F,Xi | [Risk Statements ]
10-36/37/38-22 | [Safety Statements ]
16-26-36/37/39-37 | [RIDADR ]
1993 | [WGK Germany ]
3 | [HazardClass ]
3 | [HazardClass ]
IRRITANT, FLAMMABLE | [PackingGroup ]
Ⅲ | [HS Code ]
29333990 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless Transparent Liquid | [Synthesis]
Taking 2,5-dichloropyridine as raw material, 2,5-dibromopyridine is obtained by halogenation method, and then further through methylation, we can get the product 2,5-difluoropyridine we want. The purity of this crude product can meet the general needs of |
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