| Identification | Back Directory | [Name]
3,6,9,12-tetraoxatridecylamine | [CAS]
85030-56-4 | [Synonyms]
MPEG4-NH2
m-PEG4-amine
MeO-PEG4-NH2
m-dPEG(R)4-amine
Einecs 285-182-1
Methyl-PEG4-amine
3,6,9,12-tetraoxatridecylamine
3,6,9,12-Tetraoxatridecanamine
3,6,9,12-Tetraoxatridecan-1-aMine
3,6,9,12-Tetraoxatridecane-1-amine
3,6,9,12-Tetraoxatridecanamine >
2,5,8,11-tetraoxatridecane-13-aMine
Triethylene glycol 2-aminoethyl methyl ether
2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethanamine | [EINECS(EC#)]
285-182-1 | [Molecular Formula]
C9H21NO4 | [MDL Number]
MFCD11041099 | [MOL File]
85030-56-4.mol | [Molecular Weight]
207.267 |
| Chemical Properties | Back Directory | [Boiling point ]
85°C/0.1mmHg(lit.) | [density ]
1.005±0.06 g/cm3(Predicted) | [refractive index ]
1.4440 to 1.4480 | [storage temp. ]
-20°C | [form ]
solid or viscous liquid | [pka]
8.74±0.10(Predicted) | [color ]
Colorless to Almost colorless | [InChI]
InChI=1S/C9H21NO4/c1-11-4-5-13-8-9-14-7-6-12-3-2-10/h2-10H2,1H3 | [InChIKey]
DQTQYVYXIOQYGN-UHFFFAOYSA-N | [SMILES]
C(N)COCCOCCOCCOC |
| Hazard Information | Back Directory | [Description]
m-PEG4-amine is a PEG reagent containing an amino (NH2) group. NH2 group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. | [Uses]
m-PEG4-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [reaction suitability]
reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: carboxyl reactive | [IC 50]
Cleavable Linker; PEGs | [References]
[1] Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1. |
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