| Identification | Back Directory | [Name]
m-PEG5-bromide | [CAS]
854601-80-2 | [Synonyms]
mPEG5-Br
m-PEG5-bromide
Br-(CH2CH2O)5-Me
Bromo-PEG5-methoxy
Methyl-PEG5-bromide
16-bromo-2,5,8,11,14-pentaoxahexadecane
2,5,8,11,14-Pentaoxahexadecane, 16-bromo- | [Molecular Formula]
C11H23BrO5 | [MDL Number]
MFCD28950766 | [MOL File]
854601-80-2.mol | [Molecular Weight]
315.2 |
| Chemical Properties | Back Directory | [Boiling point ]
342.4±32.0 °C(Predicted) | [density ]
1.235±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [form ]
liquid | [color ]
Colourless |
| Hazard Information | Back Directory | [Description]
m-PEG5-bromide is a PEG linker containing a bromide group. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
m-PEG5-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] Jennifer Riggs-Sauthier, et al. Oligomer-Protein Tyrosine Kinase Inhibitor Conjugates. US20120094998A1. |
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