| Identification | Back Directory | [Name]
N-(4'-Cyano-[1,1'-biphenyl]-3-yl-N-(3-pyridinylmethyl)-ethanesulfonamidehydrochloride | [CAS]
856702-40-4 | [Synonyms]
CBiPES
CBiPES HCl
CBiPES hydrochloride
N-(4'-cyanobiphenyl-3-yl)-N-(pyridin-3-ylMethyl)ethanesulfonaMide hydrochloride
N-(4'-Cyano-[1,1'-biphenyl]-3-yl-N-(3-pyridinylmethyl)-ethanesulfonamidehydrochloride | [Molecular Formula]
C21H20ClN3O2S | [MDL Number]
MFCD18086913 | [MOL File]
856702-40-4.mol | [Molecular Weight]
413.92 |
| Chemical Properties | Back Directory | [storage temp. ]
Desiccate at RT | [solubility ]
DMSO: >20mg/mL | [form ]
Powder | [color ]
off-white to light brown | [InChI]
1S/C21H19N3O2S.ClH/c1-2-27(25,26)24(16-18-5-4-12-23-15-18)21-7-3-6-20(13-21)19-10-8-17(14-22)9-11-19;/h3-13,15H,2,16H2,1H3;1H | [InChIKey]
QKUHSVQWWZBAKM-UHFFFAOYSA-N | [SMILES]
[S](=O)(=O)(N(Cc3cnccc3)c1cc(ccc1)c2ccc(cc2)C#N)CC.Cl |
| Hazard Information | Back Directory | [Uses]
CBiPES Hydrochloride is a selective positive allosteric modulator of the mGluR-2. | [Biological Activity]
CBiPES is a positive allosteric modulator of the mGlu2 receptor. CBiPES attenuates stress-induced hyperthermia and blocks the hyperlocomotor effects of PCP in murine models. In r at brainCBiPES attenuates ketamine-induced increase in extracellular histamine concentration. This compound is a sulfonamidedifferent chemical class from other mGlu2R agonists in the Sigma catalog. |
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| Company Name: |
BOC Sciences
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| Tel: |
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| Website: |
https://www.bocsci.com |
| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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