| Identification | More | [Name]
2,4-Dichloro-5-fluorobenzoyl chloride | [CAS]
86393-34-2 | [Synonyms]
2,4-DICHLORO-5-FLUOROBENZOYL CHLORIDE
2,4-Dichloro-5-Fluorosbenzoylchloride
2,4-difluoro-5-fluorobenzoyl chloride
2,4-DICHLORO-5-FLUOROBENZOYL CHLORIDE, 9 6%
2,4-Dichloro-5-fluorobenzoyl chloride 98%
2,4-Dichloro-5-fluorobenzoylchloride98%
5-FLUORO2,4-DICHLOROBENZOYLCHLORIDE
2,4-Dichlor-5-fluor-benzoylchlorid | [EINECS(EC#)]
428-390-1 | [Molecular Formula]
C7H2Cl3FO | [MDL Number]
MFCD00075341 | [Molecular Weight]
227.45 | [MOL File]
86393-34-2.mol |
| Questions And Answer | Back Directory | [Preparation]
method for synthesizing 2,4-dichloro-5-fluorobenzoyl chloride includes: preparing 2,4-dichlorofluorobenzene, carbon dioxide, and carbon tetrachloride in the presence of a cationic resin catalyst. The amount of the cationic resin catalyst is 1%–10% of the mass of 2,4-dichlorofluorobenzene. The preparation method of the cationic resin catalyst includes: treating the cationic resin with 1 mol/L sodium hydroxide, washing with hydrochloric acid, washing with water until neutral, then immersing it in a 0.5 mol/L FeCl3 solution and stirring for 5–10 hours; then adding HF to adjust the pH to 2–3; aging the reaction system at -3 to -6°C for 20–30 hours, filtering and washing, and then drying the filter cake at 70–90°C to obtain the cationic resin catalyst. | [Uses]
2,4-Dichloro-5-fluorobenzoyl chloride is a major raw material for the preparation of antipsychotic drugs trifluoroguanidine alcohol, trifluoroguanidine, pentafluorolido, and the synthesis of broad-spectrum antibiotics such as ciprofloxacin and other third-generation quinolone drugs. It can also be used in pesticides, insecticides, ovicides, and the identification of plastics and resins. |
| Chemical Properties | Back Directory | [Boiling point ]
143-144 °C35 mm Hg(lit.)
| [density ]
1.568 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.572(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
RT, stored under nitrogen | [form ]
clear liquid | [color ]
Colorless to Light yellow | [Specific Gravity]
1.568 | [Sensitive ]
Moisture Sensitive | [BRN ]
4989077 | [InChI]
InChI=1S/C7H2Cl3FO/c8-4-2-5(9)6(11)1-3(4)7(10)12/h1-2H | [InChIKey]
RPZXUSJCSDQNTE-UHFFFAOYSA-N | [SMILES]
C(Cl)(=O)C1=CC(F)=C(Cl)C=C1Cl | [CAS DataBase Reference]
86393-34-2(CAS DataBase Reference) |
|
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J & K SCIENTIFIC LTD.
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Alfa Aesar
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400-6106006 |
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Energy Chemical
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Jia Xing Isenchem Co.,Ltd
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