| Identification | Back Directory | [Name]
CGP 52608 | [CAS]
87958-67-6 | [Synonyms]
CGP 52608
CGP 52608 >=98%, solid
1-[3-Allyl-4-oxo-thiazolidine-2-ylidene]-4-methyl-thiosemicarbazone
N-Methyl-2-[4-oxo-3-(2-propen-1-yl)-2-thiazolidinylidene]-hydrazinecarbothioamide
Hydrazinecarbothioamide, N-methyl-2-[4-oxo-3-(2-propen-1-yl)-2-thiazolidinylidene]- | [Molecular Formula]
C8H12N4OS2 | [MDL Number]
MFCD00942304 | [MOL File]
87958-67-6.mol | [Molecular Weight]
244.34 |
| Hazard Information | Back Directory | [Uses]
CGP 52608 has been used as a RAR related orphan receptor α (RORα) synthetic agonist in THP-1 macrophages, in human monocyte cells THP1 and somatic testicular cells. | [Biochem/physiol Actions]
CGP 52608 is a thiazolidine derivative and an antiarthritic compound. It possesses immunostimulatory functionality and elicits antiproliferative effect in colon tumors. It is cytotoxic towards neural cell lines. CGP 52608 induces apoptosis in tumor and also favors G0-G1 cell cycle phase accumulation in neural cell lines. |
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| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|