| Identification | More | [Name]
2-Isopropylphenol | [CAS]
88-69-7 | [Synonyms]
2-HYDROXYCUMENE
2-HYDROXYCUMOL
2-ISOPROPYLPHENOL
FEMA 3461
O-CUMENOL
OIPP
O-ISOPROPYLPHENOL
ORTHO-ISO-PROPYLPHENOL
1-Hydroxy-2-isopropylbenzene
2-(1-methylethyl)-pheno
2-(1-Methylethyl)phenol
2-(1-methylethyl)-Phenol
Isopropylphenol, ortho
o-Hydroxycumene
o-isopropyl-pheno
Phenol, o-isopropyl-
Phenol,2-(1-methylethyl)-
Phenol,o-isopropyl-
Prodox 131
prodox131 | [EINECS(EC#)]
201-852-8 | [Molecular Formula]
C9H12O | [MDL Number]
MFCD00002224 | [Molecular Weight]
136.19 | [MOL File]
88-69-7.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR SLIGHTLY YELLOW LIQUID | [Melting point ]
12-16 °C (lit.) | [Boiling point ]
212-213 °C (lit.) | [density ]
1.012 g/mL at 25 °C(lit.)
| [vapor pressure ]
<0.05 mm Hg ( 25 °C)
| [FEMA ]
3461 | [refractive index ]
n20/D 1.526(lit.)
| [Fp ]
192 °F
| [storage temp. ]
Store below +30°C. | [solubility ]
insoluble | [form ]
Liquid | [pka]
10.49±0.10(Predicted) | [color ]
Clear slightly yellow | [Odor]
at 0.10 % in propylene glycol. medicinal creosote phenolic | [biological source]
synthetic | [Odor Type]
phenolic | [Water Solubility ]
insoluble | [JECFA Number]
697 | [BRN ]
1363322 | [Henry's Law Constant]
2.6×100 mol/(m3Pa) at 25℃, Mackay et al. (2006) | [InChI]
1S/C9H12O/c1-7(2)8-5-3-4-6-9(8)10/h3-7,10H,1-2H3 | [InChIKey]
CRBJBYGJVIBWIY-UHFFFAOYSA-N | [SMILES]
CC(C)c1ccccc1O | [LogP]
2.82 | [CAS DataBase Reference]
88-69-7(CAS DataBase Reference) | [NIST Chemistry Reference]
Phenol, 2-(1-methylethyl)-(88-69-7) | [EPA Substance Registry System]
88-69-7(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS05 | [Signal word ]
Danger | [Hazard statements ]
H314 | [Precautionary statements ]
P280-P303+P361+P353-P305+P351+P338+P310 | [Hazard Codes ]
C,Xn | [Risk Statements ]
R34:Causes burns.
R22:Harmful if swallowed. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) . | [RIDADR ]
UN 3145 8/PG 2
| [WGK Germany ]
3
| [RTECS ]
SL5900000
| [TSCA ]
Yes | [REACH Registrations]
Active | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29071900 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Dam. 1
Skin Corr. 1B |
| Hazard Information | Back Directory | [General Description]
Light-yellow liquid. Less dense than water and insoluble in water. Hence floats on water. | [Reactivity Profile]
Phenols, such as O-ISOPROPYL PHENOL(88-69-7), do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid. Nitrated phenols often explode when heated. Special Hazards of Combustion Products: Irritating vapors and toxic gases, such as carbon dioxide and carbon monoxide, may be formed when involved in fire [USCG, 1999]. | [Air & Water Reactions]
Insoluble in water. | [Health Hazard]
Exposure can cause irritation of eyes, nose and throat. | [Fire Hazard]
Special Hazards of Combustion Products: Irritating vapors and toxic gases, such as carbon dioxide and carbon monoxide, may be formed when involved in fire. | [Description]
2-Isopropylphenol is medicinal, creosote. | [Chemical Properties]
2-Isopropylphenol has a medicinal, creosote odor | [Chemical Properties]
CLEAR SLIGHTLY YELLOW LIQUID | [Occurrence]
Reported found in Japanese whiskey, Romano cheese and dried bonito | [Uses]
2-Isopropylphenol was used to study the ability of 2-isopropylphenol to activate estrogen receptor (ER), androgen receptor (AR), progesterone receptor (PR) and estrogen-related receptor (ERR). | [Uses]
2-Isopropylphenol is an impurity of Propofol (P829750). | [Definition]
ChEBI: A member of the class of phenols carrying an isopropyl group at position 2. | [Aroma threshold values]
Detection: 1 ppb
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