ChemicalBook--->CAS DataBase List--->6093-68-1

6093-68-1

6093-68-1 Structure

6093-68-1 Structure
IdentificationMore
[Name]

6-HYDROXYCOUMARIN
[CAS]

6093-68-1
[Synonyms]

-HYDROXYCOUMARIN
6-hydroxy CourMarin
6-Hydroxycoumarin 97%
6-hydroxychromen-2-one
HYDROXYCOUMARIN, 6-(RG)
6-HYDROXY-2H-CHROMEN-2-ONE
6-Hydroxy-2H-chromen-2-one 97%
6-Hydroxy-2H-1-benzopyran-2-one
2H-1-Benzopyran-2-one, 6-hydroxy-
[Molecular Formula]

C9H6O3
[MDL Number]

MFCD00630040
[Molecular Weight]

162.14
[MOL File]

6093-68-1.mol
Chemical PropertiesBack Directory
[Melting point ]

249-253 °C (lit.)
[Boiling point ]

248.82°C (rough estimate)
[density ]

1.2500
[refractive index ]

1.5380 (estimate)
[storage temp. ]

Sealed in dry,Room Temperature
[pka]

8.92±0.20(Predicted)
[λmax]

349nm(EtOH)(lit.)
[LogP]

0.650 (est)
[CAS DataBase Reference]

6093-68-1(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xn,Xi
[Risk Statements ]

R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[Hazard Note ]

Irritant
[HS Code ]

29322010
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Hydrazine hydrate-->Ferric chloride-->6-aminocoumarin
Hazard InformationBack Directory
[Description]

6-Hydroxycoumarin is a coumarin which has anti-inflammatory, anti-pyretic, anti-oxidant, vasodilator, anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic and antitumor activity.
[Occurrence]

6-Hydroxycoumarin is a natural product found in Grevillea robusta and Amburana cearensis with data available.
[Uses]

6-Hydroxycoumarin (cas# 6093-68-1) is a compound useful in organic synthesis.
[Preparation]

(1) synthesis of 6-aminocoumarins:In polar solvent, using 6- nitroscumarin as raw material, using hydrazine hydrate as hydrogen Source, is reducing catalyst using ferric chloride (FeCl36H2O), at ambient pressure reduces 6-nitroscumarin, prepare 6- aminocoumarins;
(2) synthesis of 6-Hydroxycoumarins:In sulfuric acid solution, one-step method is by 6-aminocoumarins after diazo-reaction Direct hydrolysis, prepares 6-Hydroxycoumarins in high yield.
The preparation method of 6 Hydroxycoumarins
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

6093-68-1(sigmaaldrich)
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