| Identification | More | [Name]
9-Hydroxyxanthene | [CAS]
90-46-0 | [Synonyms]
9H-XANTHEN-9-OL
9-HYDROXYXANTHENE
9-Hydroxyxanthene,10% methylalcohol solution
9-XANTHENOL
9-XANTHYDROL
HYDROXYXANTHENE(9-)
XANTHANOL
Xanthanol,10%methyl alcohol solution
XANTHEN-9-OL
XANTHYDROL
9H-Xanthen-9-oll
Hydroxyxanthene
XANTHYDROL R. G., REAG. PH. EUR.
XANTHYDROL SOLUTION, PACKAGE WITH 100 ML ,~10% IN METHANOL
9-HYDROXYXANTHENE, 98+%
XANTHYDROL (10% IN METHANOL)
Xanthene-9-OL
xanthydrol solution
XANTHYDROL,REAGENT
9-Hydroxyxanthene, 9-Xanthenol | [EINECS(EC#)]
201-996-1 | [Molecular Formula]
C13H10O2 | [MDL Number]
MFCD00005057 | [Molecular Weight]
198.22 | [MOL File]
90-46-0.mol |
| Chemical Properties | Back Directory | [Definition]
A derivative of xanthene | [Appearance]
white powder | [Melting point ]
122-124 °C
| [Boiling point ]
275.53°C (rough estimate) | [density ]
0.83 g/mL at 20 °C
| [refractive index ]
1.6620 (estimate) | [Fp ]
11 °C | [storage temp. ]
2-8°C
| [solubility ]
methanol: 0.1 g/mL, clear
| [form ]
Crystalline Powder | [pka]
13.57±0.20(Predicted) | [color ]
White to off-white | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents. | [Sensitive ]
Light Sensitive | [BRN ]
10395 | [InChI]
1S/C13H10O2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8,13-14H | [InChIKey]
JFRMYMMIJXLMBB-UHFFFAOYSA-N | [SMILES]
OC1c2ccccc2Oc3ccccc13 | [LogP]
2.270 (est) | [CAS DataBase Reference]
90-46-0(CAS DataBase Reference) | [EPA Substance Registry System]
90-46-0(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
  
GHS02,GHS06,GHS08 | [Signal word ]
Danger | [Hazard statements ]
H225-H301+H311+H331-H370 | [Precautionary statements ]
P210-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311 | [Hazard Codes ]
F,T,Xi,Xn | [Risk Statements ]
R11:Highly Flammable.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R39/23/24/25:Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed .
R40:Limited evidence of a carcinogenic effect. | [Safety Statements ]
S7:Keep container tightly closed .
S16:Keep away from sources of ignition-No smoking .
S24:Avoid contact with skin .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S22:Do not breathe dust . | [RIDADR ]
UN 1230 3/PG 2
| [WGK Germany ]
3
| [RTECS ]
ZD5710000
| [F ]
8-10-23 | [Hazard Note ]
Irritant | [TSCA ]
Yes | [HS Code ]
29329990 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [Chemical Properties]
White powder.Insoluble in
water; soluble in alcohol. | [Application]
Xanthydrol may be used as a derivatization agent for the following:
Analysis of urea in urine and wine samples using high-performance liquid chromatography (HPLC) technique.
Analysis of trace levels of carbamate pesticides in surface water by gas chromatography–mass spectrometry (GC-MS). | [Uses]
Intermediate in the preparation of Propantheline Bromide. | [Preparation]
synthesis of xanthydrol: The amalgam sodium in dry toluene was warmed to 50°C, the xanthone-ethanol suspension was added, and the temperature was rapidly raised to 60-70°C with vigorous stirring. After the reaction is completed, the mercury is separated. The reaction solution was filtered, the filtrate was poured into the stirred blue distilled water, the 9-hydroxyxanthene was filtered out, washed with water, and dried to obtain the finished product with a yield of 91-95%. | [Reactions]
9-Hydroxyxanthene (xanthydrol) reacts with a variety of proteins and inactivates certain enzymes. The research data indicate that in acetic acid solution xanthydrol reacts with the following amino acids: arginine, asparagine, cysteine, glutamine, histidine, lysine, and tryptophan. The a-amino group of cu-amino acids does not react with xanthydrol under these conditions, since alanine, serine, isoleucinc, and tyrosine failed to react[1]. | [General Description]
Xanthydrol is also known as 9H-xanthen-9-ol. | [Purification Methods]
Crystallise xanthydrol from EtOH and dry it at 40-50o. [Beilstein 17 H 129, 17 I 72, 17 II 146, 17 III/IV 1602, 17/4 V 502.] | [References]
[1] REACTIONS OF XANTHYDROL. 1954.
[2] Tu Q et al. Quantification ethyl carbamate in wines using reaction-assisted-extraction with 9-xanthydrol and detection by heart-cutting multidimensional gas chromatography-mass spectrometry. Analytica Chimica Acta, 2018; 1001: 86-92. |
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Energy Chemical
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Spectrum Chemical Manufacturing Corp.
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