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79-14-1

79-14-1 Structure

79-14-1 Structure
IdentificationMore
[Name]

Glycolic acid
[CAS]

79-14-1
[Synonyms]

2-HYDROXYACETIC ACID
AKOS BBS-00004277
GLYCOLATE IC STANDARD
GLYCOLIC ACID
GLYCOLLIC ACID
HYDROXYACETIC ACID
HYDROXYETHANOIC ACID
RARECHEM AL BO 0466
Aceticacid,hydroxy-
acidehydroxyacetique
alpha-Hydroxyacetic acid
alpha-hydroxyaceticacid
glycolic
glycolicacid,solution
HOCH2COOH
hydroxy-aceticaci
Kyselina glykolova
Kyselina hydroxyoctova
kyselinaglykolova
kyselinahydroxyoctova
[EINECS(EC#)]

201-180-5
[Molecular Formula]

C2H4O3
[MDL Number]

MFCD00004312
[Molecular Weight]

76.05
[MOL File]

79-14-1.mol
Chemical PropertiesBack Directory
[Appearance]

colourless crystalline solid
[mp ]

75-80 °C(lit.)
[bp ]

112 °C
[density ]

1.25 g/mL at 25 °C
[refractive index ]

n20/D 1.424
[Fp ]

112°C
[solubility ]

H2O: 0.1 g/mL, clear
[Stability:]

Stable. Incompatible with bases, oxidizing agents and reducing agents.
[Water Solubility ]

SOLUBLE
[Sensitive ]

Hygroscopic
[Merck ]

14,4498
[BRN ]

1209322
[Uses]

glycolic acid (hydroxyacetic acid) reduces corenocyte cohesion and corneum layer thickening where an excess buildup of dead skin cells can be associated with many common skin problems, such as acne, dry and severely dry skin, and wrinkles. glycolic acid acts by dissolving the internal cellular cement responsible for abnormal keratinization, facilitating the sloughing of dead skin cells. It also improves skin hydration by enhancing moisture uptake as well as increasing the skin’s ability to bind water. This occurs in the cellular cement through an activation of glycolic acid and the skin’s own hyaluronic acid content. Hyaluronic acid is known to retain an impressive amount of moisture and this capacity is enhanced by glycolic acid. As a result, the skin’s own ability to raise its moisture content is increased. glycolic acid is the simplest alpha hydroxyacid (AHA). It is also the AHA that scientists and formulators believe has greater penetration potential largely due to its smaller molecular weight. It is mildly irritating to the skin and mucous membranes if the formulation contains a high glycolic acid concentration and/ or a low pH. glycolic acid proves beneficial for acne-prone skin as it helps keep pores clear of excess keratinocytes. It is also used for diminishing the signs of age spots, as well as actinic keratosis. However, glycolic acid is most popularly employed in anti-aging cosmetics because of its hydrating, moisturizing, and skin-normalizing abilities, leading to a reduction in the appearance of fine lines and wrinkles. Regardless of the G skin type, glycolic acid use is associated with softer, smoother, healthier, and younger looking skin. glycolic acid is naturally found in sugarcane but synthetic versions are most often used in cosmetic formulations.
[CAS DataBase Reference]

79-14-1(CAS DataBase Reference)
[NIST Chemistry Reference]

Acetic acid, hydroxy-(79-14-1)
[EPA Substance Registry System]

79-14-1(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

C
[Risk Statements ]

R34:Causes burns.
R22:Harmful if swallowed.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
[RIDADR ]

UN 3265 8/PG 3
[WGK Germany ]

1
[RTECS ]

MC5250000
[HazardClass ]

8
[PackingGroup ]

II
[HS Code ]

29181990
[Hazardous Substances Data]

79-14-1(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Sodium hydroxide-->CARBON DIOXIDE-->Sodium cyanide-->HYDROGEN CYANIDE-->Methyl glycolate
[Preparation Products]

Chloroacetic acid-->Ethylenediaminetetraacetic acid-->Acemetacin-->Mefenacet-->1H-BENZIMIDAZOLE-2-CARBONYL CHLORIDE HYDROCHLORIDE-->PGA and its copolymer-->Methyl glycolate-->Indole-3-acetic acid-->Acetoxyacetyl chloride-->2-Benzimidazolecarboxylic acid-->2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate -->1H-Benzimidazole-2-methanol
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

hydroxyacetic acid(79-14-1).msds
Questions And AnswerBack Directory
[Description]

Glycolic acid is the smallest alpha-hydroxy acid (AHA). It is mainly supplemented to various skin-care products to improve the skin’s appearance and texture. It can also reduce wrinkles, acne scarring, and hyperpigmentation. In textile industry, it can be used as a dyeing and tanning agent. It can also be used as a flavoring agent in food processing, and as a skin care agent in the pharmaceutical industry. It can also be added into emulsion polymers, solvents and ink additives to improve flow properties and impart gloss. Moreover, it is a useful intermediate for organic synthesis including oxidative-reduction, esterification and long chain polymerization.
[References]

Bhatia, A. C., and F. Jimenez. "Rapid treatment of mild acne with a novel skin care system containing 1% salicylic acid, 10% buffered glycolic acid, and botanical ingredients." Journal of Drugs in Dermatology Jdd13.6(2014):678-83.
https://en.wikipedia.org/wiki/Glycolic_acid
https://pubchem.ncbi.nlm.nih.gov/compound/glycolic_acid#section=Top
Spectrum DetailBack Directory
[Spectrum Detail]

Glycolic acid(79-14-1)Raman
Glycolic acid(79-14-1)1HNMR
Glycolic acid(79-14-1)13CNMR
Glycolic acid(79-14-1)IR1
Glycolic acid(79-14-1)IR2
Glycolic acid(79-14-1)MS
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Glycolic acid, 99%(79-14-1)
[Alfa Aesar]

Glycolic acid, ca 67% aq. soln.(79-14-1)
[Sigma Aldrich]

79-14-1(sigmaaldrich)
[TCI AMERICA]

Glycolic Acid,>98.0%(T)(79-14-1)
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