| Identification | Back Directory | [Name]
DEXTRANASE | [CAS]
9025-70-1 | [Synonyms]
DEXTRANASE
EC 3.2.1.11
IUB: 3.2.1.11
Dextranase Plus L
dextranase partially purified
dextranase from penicillium sp.
Dextranase Paecilomyces lilacinus
1,6-α-d-glucan 6-glucanohydrolase
MPB Dextranase,from Penicillium sp
dextranase from A penicillium species
1,6-ALPHA-D-GLUCAN 6-GLUCANOHYDROLASE
1,6-ALPHA-D-GLUCAN-L-GLUCANOHYDROLASE
dextranase from paecilomyces lilacinus
DextranaseExCultureFiltrateOfASelected
Dextranase from Chaetomium erraticum
dextranase crude from A penicillium*species
DEXTRANASE FROM PAECILOMYCES LILACINUS, ~60 U/MG
Dextranase from Penicillium sp.,1,6-α-D-Glucan 6-glucanohydrolase | [EINECS(EC#)]
232-803-9 | [Molecular Formula]
NULL | [MDL Number]
MFCD00130940 |
| Hazard Information | Back Directory | [Chemical Properties]
It can break down high-molecular-weight, viscous glucans into low-viscosity isomaltose and isomaltotriose. It also hydrolyzes the 1,3-β- and 1,4-β-glycosidic bonds in β-D-glucans into oligosaccharides and glucose. The optimal pH for activity is 6.0-6.5 for bacterial production and 4.0-4.5 for fungal production. It is generally stable at pH 6-9. If kept at pH 8.0 and 35°C for 3 hours, its activity remains essentially unchanged. However, it decreases by approximately 20% at 45°C and by 70% at 50°C. It is extremely stable in the presence of calcium ions in aqueous solution, and its heat resistance is also enhanced. Glycerol helps prevent a decrease in activity, and is most effective at a concentration of 40%-60%. Surfactants can reduce its activity. The product is an off-white amorphous powder or liquid, which may contain a carrier or diluent. It is soluble in water and essentially insoluble in ethanol, chloroform, and ether. | [Uses]
Dextranase from Chaetomium erraticum has been used:
- in microcarrier dissolution to produce multicellular 3D spheroids for drug discovery
- in in vitro digestion of extracellular polysaccharide (EPS) from the bacterial isolates
- in a study to investigate the immobilization of dextranase
- to investigate the optimization of process conditions for enzymatic modification of alternan
| [Uses]
Dextranase from Penicillium sp has been used:
- in the digestion of exopolysaccharides from P. aeruginosa biofilms and dextran polymers
- as a component of trypticase soy broth (TSYPS) for Streptococcus mutans culture
- in microgel degradation
| [Uses]
Dextranase can be used in preparation of dextran for clinical use.
| [General Description]
Dextranase from fungi belong to the glycoside hydrolase families (GH) 49. Dextranase from Penicillium sp. are stable at varying temperature and pH. | [Biochem/physiol Actions]
An endodextranase that hydrolyzes -(1,6)-glucosidic linkages in dextran. Dextrans are undesirable compounds synthesized from sucrose by microbial contaminants during sugar production that increase viscosity of the flow and decrease industrial recovery. Dextranase has been used for hydrolyzing dextran at sugar mills in order to improve efficiency of sugar production. |
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