| Identification | Back Directory | [Name]
Tofogliflozin | [CAS]
903565-83-3 | [Synonyms]
CSG 452
Tofogliflozin
CSG452;CSG-452
Tofogliflozin-13C6
Tofogliflozin(free)
CSG452; CSG 452; CSG-452
(3S,3'R,4'S,5'S,6'R)-5-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol
(1S,3'R,4'S,5'S,6'R)-6'-(hydroxymethyl)-6-(methoxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-3',4',5'-triol
((1S,3'R,4'S,5'S,6'R)-6-(4-ethylbenzyl)-3',4',5'-trihydroxy-3',4',5',6'-tetrahydro-3H-spiro[isobenzofuran-1,2'-pyran]-6'-yl)methyl propionate
(1S,3'R,4'S,5'S,6'R)-6-[(4-Ethylphenyl)Methyl]-3',4',5',6'-tetrahydro-6'-(hydroxyMethyl)spiro[isobenzofuran-1(3H),2'-[2H]pyran]-3',4',5'-triol
Spiro[isobenzofuran-1(3H),2'-[2H]pyran]-3',4',5'-triol, 6-[(4-ethylphenyl)methyl]-3',4',5',6'-tetrahydro-6'-(hydroxymethyl)-, (1S,3'R,4'S,5'S,6'R)- | [Molecular Formula]
C22H26O6 | [MOL File]
903565-83-3.mol | [Molecular Weight]
386.44 |
| Chemical Properties | Back Directory | [Melting point ]
75-79oC | [Boiling point ]
607.5±55.0 °C(Predicted) | [density ]
1.38±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.06±0.70(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
A novel, potent, and highly selective SGLT2 inhibitor that has been shown to improve glycemic control in diabetic mice and rats. | [Definition]
ChEBI: Tofogliflozin is a member of 2-benzofurans. |
|
|