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90419-12-8

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90419-12-8 Structure

90419-12-8 Structure
IdentificationBack Directory
[Name]

PANCREATIC POLYPEPTIDE, RAT
[CAS]

90419-12-8
[Synonyms]

PP, RAT
Rat pancreatic polypeptide
PANCREATIC POLYPEPTIDE, RAT
Pancreatic polypeptide(rat) (9CI)
Pancreatic Polypeptide rat, ≥95% (HPLC)
APLEPMYPGDYATHEQRAQYETQLRRYINTLTRPRY-NH2
Pancreatic Polypeptide ratPancreatic Polypepti
ALA-PRO-LEU-GLU-PRO-MET-TYR-PRO-GLY-ASP-TYR-ALA-THR-HIS-GLU-GLN-ARG-ALA-GLN-TYR
ALA-PRO-LEU-GLU-PRO-MET-TYR-PRO-GLY-ASP-TYR-ALA-THR-HIS-GLU-GLN-ARG-ALA-GLN-TYR-GLU-THR-GLN-LEU-ARG-ARG-TYR-ILE-ASN-THR-LEU-THR-ARG-PRO-ARG-TYR-NH2
Ala-Pro-Leu-Glu-Pro-Met-Tyr-Pro-Gly-Asp-Tyr-Ala-Thr-Ala-Thr-His-Glu-Gln-Arg-Ala-Gln-Tyr-Glu-Thr-Gln-Leu-Arg-Arg-Tyr-Ile-Asn-Thr-Leu-Thr-Arg-Tyr-NH2
H-ALA-PRO-LEU-GLU-PRO-MET-TYR-PRO-GLY-ASP-TYR-ALA-THR-HIS-GLU-GLN-ARG-ALA-GLN-TYR-GLU-THR-GLN-LEU-ARG-ARG-TYR-ILE-ASN-THR-LEU-THR-ARG-PRO-ARG-TYR-NH2
REF DUPL: Ala-Pro-Leu-Glu-Pro-Met-Tyr-Pro-Gly-Asp-Tyr-Ala-Thr-His-Glu-Gln-Arg-Ala-Gln-Tyr-Glu-Thr-Gln-Leu-Arg-Arg-Tyr-Ile-Asn-Thr-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
[Molecular Formula]

C195H298N58O57S1
[MDL Number]

MFCD00081813
[Molecular Weight]

4398.87
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

Soluble in DMSO
[Sequence]

Ala-Pro-Leu-Glu-Pro-Met-Tyr-Pro-Gly-Asp-Tyr-Ala-Thr-His-Glu-Gln-Arg-Ala-Gln-Tyr-Glu-Thr-Gln-Leu-Arg-Arg-Tyr-Ile-Asn-Thr-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Pancreatic Polypeptide, rat is an agonist of NPY receptor, with high affinity at NPYR4.
[in vivo]

Pancreatic Polypeptide (25 nmol/kg bw, i.p.) reduces glucose-stimulated insulin concentrations but shows no effect on acute feeding behaviour in overnight fasted mice[1].

[storage]

Store at -20°C
[References]

[1] Khan D, et al. Influence of neuropeptide Y and pancreatic polypeptide on islet function and beta-cell survival. Biochim Biophys Acta. 2017 Apr;1861(4):749-758. DOI:10.1016/j.bbagen.2017.01.005
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