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53749-61-4

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53749-61-4 Structure

53749-61-4 Structure
IdentificationBack Directory
[Name]

SUBSTANCE P (2-11)
[CAS]

53749-61-4
[Synonyms]

DECA-SUBSTANCE P
2-11-Substance P
SUBSTANCE P (2-11)
Substance P, fragment 2-11
substance P fragment 2-11 acetate
Substance-P-(2-11)Deca-Substance P
PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2
H-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2
PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2: PQQFFGLM-NH2
SUBSTANCE P(2-11) TRIFLUOROACETATE SALT (DECA-SUBSTANCE P, SP
[Molecular Formula]

C57H86N14O12S
[MDL Number]

MFCD00076791
[MOL File]

53749-61-4.mol
[Molecular Weight]

1191.44
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[form ]

Solid
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Substance P (2-11) is a substance P (SP) fragment peptide. Substance P (2-11) has contracting activities on guinea pig ileum. Substance P (2-11) inhibits the permeation of 3H SP in BBMEC monolayers[1][2].
[References]

[1] Yanaihara N, et al. Immunological aspects of secretin, substance P, and VIP. Gastroenterology. 1977 Apr;72(4 Pt.2):803-10. PMID:838240
[2] Chappa AK, et al. Characteristics of substance P transport across the blood-brain barrier. Pharm Res. 2006 Jun;23(6):1201-8. DOI:10.1007/s11095-006-0068-1
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