| Identification | Back Directory | [Name]
SUBSTANCE P (1-4) | [CAS]
57468-16-3 | [Synonyms]
ARG-PRO-LYS-PRO SUBSTANCE P (1-4) H-ARG-PRO-LYS-PRO-OH substance P fragment 1-4 L-Arg-L-Pro-L-Lys-L-Pro-OH L-Arginyl-L-prolyl-L-lysyl-L-proline Substance P Fragment 1-4 acetate salt L-Proline, L-arginyl-L-prolyl-L-lysyl- substancepfragment1-4actsonphagocytosis ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY: RPKPQQFFG SUBSTANCE P FRAGMENT 1-4 ACETATE SALTSUBSTANCE P FRAGMEN | [Molecular Formula]
C22H40N8O5 | [MDL Number]
MFCD00080123 | [MOL File]
57468-16-3.mol | [Molecular Weight]
496.6 |
| Hazard Information | Back Directory | [Uses]
Substance P(1-4) is a potent neurokinin receptors (NK-R) antagonist. Substance P(1-4) has regulation of normal hematopoiesis and inhibits endogenous erythroid colony (EEC) formation[1]. | [References]
[1] Le Gall C, et, al. Inhibitory effect of the substance P and its derivative on erythropoietin-independent growth of erythroid progenitors in polycythemia vera. Leuk Res. 2008 May;32(5):743-54. DOI:10.1016/j.leukres.2007.09.011 |
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