ChemicalBook--->CAS DataBase List--->924-42-5

924-42-5

924-42-5 Structure

924-42-5 Structure
IdentificationMore
[Name]

N-Methylolacrylamide
[CAS]

924-42-5
[Synonyms]

METHYLOLACRYLAMIDE
n-(hydroxymethyl)-2-propenamide
N-(HYDROXYMETHYL)ACRYLAMIDE
N-METHYLOLACRYLAMIDE
2-Propenamide,N-(hydroxymethyl)-
Acrylamide, N-(hydroxymethyl)-
Monomethylolacrylamide
n-(hydroxymethyl)-2-propenamid
n-(hydroxymethyl)-acrylamid
NCI-C60333
NM-AMD
N-Methanolacrylamide
N-Methyloacrylamide
n-methylolacrylamide(48%inwater)
Uramine T 80
uraminet80
Yuramin T 80
Methylolacrylamidesolution
N-MAN
N-(HYDROXYMETHYL)ACRYLAMIDE SOLUTION, ST AB., ~48% IN H2O
[EINECS(EC#)]

213-103-2
[Molecular Formula]

C4H7NO2
[MDL Number]

MFCD00004597
[Molecular Weight]

101.1
[MOL File]

924-42-5.mol
Chemical PropertiesBack Directory
[Melting point ]

74-75°C
[Boiling point ]

277°C(lit.)
[density ]

1.082 g/mL at 20 °C
[vapor pressure ]

31 hPa (25 °C)
[refractive index ]

n20/D 1.413
[Fp ]

100°C
[storage temp. ]

Refrigerator
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

13.25±0.10(Predicted)
[color ]

White to Off-White
[Specific Gravity]

1.074
[PH]

6.0-7.0 (H2O, 20°C)
[Water Solubility ]

<0.1 g/100 mL at 20.5 ºC
[BRN ]

506646
[Stability:]

Light Sensitive, Moisture Sensitive
[InChI]

1S/C4H7NO2/c1-2-4(7)5-3-6/h2,6H,1,3H2,(H,5,7)
[InChIKey]

CNCOEDDPFOAUMB-UHFFFAOYSA-N
[SMILES]

OCNC(=O)C=C
[LogP]

-1.81 at 20℃ and pH7
[CAS DataBase Reference]

924-42-5(CAS DataBase Reference)
[IARC]

3 (Vol. 60) 1994
[NIST Chemistry Reference]

2-Propenamide, n-(hydroxymethyl)-(924-42-5)
[EPA Substance Registry System]

924-42-5(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS06,GHS08
[Signal word ]

Danger
[Hazard statements ]

H301-H317-H340-H350-H361-H372-H373
[Precautionary statements ]

P202-P260-P264-P280-P301+P310-P302+P352
[Hazard Codes ]

Xn
[Risk Statements ]

R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[RIDADR ]

2810
[WGK Germany ]

3
[RTECS ]

AS3600000
[TSCA ]

TSCA listed
[REACH Registrations]

Active
[HazardClass ]

4.1
[PackingGroup ]

III
[HS Code ]

29241990
[Storage Class]

6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects
[Hazard Classifications]

Acute Tox. 3 Oral
Carc. 1B
Muta. 1B
Repr. 2
Skin Sens. 1
STOT RE 1
STOT RE 2 Oral
[Hazardous Substances Data]

924-42-5(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Formaldehyde-->Acrylonitrile-->Acrylamide
[Preparation Products]

Adhesive for nonwoven fabric-->Binder for coating printing
Hazard InformationBack Directory
[General Description]

A colorless or yellow aqueous solution.
[Reactivity Profile]

N-METHYLOLACRYLAMIDE(924-42-5) may be sensitive to prolonged exposure to light. Polymerization and generation of heat and flames may occur on exposure to to heat or contaminants. Incompatible with strong oxidizers.
[Air & Water Reactions]

Soluble in water.
[Fire Hazard]

Literature sources indicate that this chemical is nonflammable.
[Chemical Properties]

White solid
[Uses]

N-(Hydroxymethyl)acrylamide can be used as:
  • A monomer in the development of polymer gel dosimeters specifically designed for radiation therapy applications. The incorporation of NHMA enhances the sensitivity of the dosimeter to radiation doses.
  • A monomer in the development of thermo-responsive polymeric gates, which exhibits thermo-responsive behavior. The incorporation of NHMA enhances the overall properties of the polymer, allowing for better control over the release mechanisms in response to temperature changes.
  • A key monomer in the synthesis of double-hydrophilic and amphiphilic block glycopolymers, contributing to their self-assembly properties, biocompatibility, and functionalization potential. These characteristics make NHMA-based glycopolymers valuable for various biomedical applications, including drug delivery systems, biosensors, and tissue engineering.
[Definition]

ChEBI: N-Methylolacrylamide is a secondary carboxamide.
[Synthesis]

(1), the acrylamide is added to the reaction kettle containing solvent acetone, the polymerization blocking agent is added, and the temperature is raised to 42~45℃;

(2), adding catalyst sodium methanol, adjusting the pH value in the reaction so

Material Safety Data Sheet(MSDS)Back Directory
[msds information]

N-(Hydroxymethyl)acrylamide(924-42-5).msds
Spectrum DetailBack Directory
[Spectrum Detail]

N-Methylolacrylamide(924-42-5)MS
N-Methylolacrylamide(924-42-5)1HNMR
N-Methylolacrylamide(924-42-5)13CNMR
N-Methylolacrylamide(924-42-5)IR1
N-Methylolacrylamide(924-42-5)IR2
N-Methylolacrylamide(924-42-5)Raman
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

924-42-5(sigmaaldrich)
[TCI AMERICA]

N-(Hydroxymethyl)acrylamide,>98.0%(T)(924-42-5)
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