| Identification | Back Directory | [Name]
Propargyl-PEG3-Ms | [CAS]
943726-01-0 | [Synonyms]
Propargyl-PEG3-Ms
Propargyl-PEG2-Ms
Ethanol, 2-[2-(2-propyn-1-yloxy)ethoxy]-, 1-methanesulfonate | [Molecular Formula]
C8H14O5S | [MDL Number]
MFCD29042346 | [MOL File]
943726-01-0.mol | [Molecular Weight]
222.26 |
| Hazard Information | Back Directory | [Description]
Propargyl-PEG3-Ms is a crosslinking reagent with a propargyl group and a mesyl group. The propargyl group reacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions. | [Uses]
Propargyl-PEG2-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-MS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] Bai S, et al. Synthesis and structure-activity relationship studies of conformationally flexibletetrahydroisoquinolinyl triazole carboxamide and triazole substituted benzamide analogues as σ2 receptor ligands. J Med Chem. 2014 May 22;57(10):4239-51. DOI:10.1021/jm5001453 |
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