ChemicalBook--->CAS DataBase List--->979-88-4

979-88-4

979-88-4 Structure

979-88-4 Structure
IdentificationMore
[Name]

2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt
[CAS]

979-88-4
[Synonyms]

2,2'-BICINCHONINIC ACID DISODIUM SALT
2,2'-BIQUINOLINE-4,4'-DICARBOXYLIC ACID DISODIUM SALT
2,2'-BIQUINOLINE-4,4'-DICARBOXYLIC ACID DISODIUM SALT TRIHYDRATE
4,4'-DICARBOXY-2,2'-BIQUINOLINE DISODIUM SALT
4,4'-DICARBOXY-2,2'-BIQUINOLINE, SODIUM SALT
BCA
BCA DISODIUM SALT
BICINCHONINIC ACID DISODIUM SALT
BICINCHONINIC ACID DISODIUM SALT HYDRATE
DI-SODIUM 2,2'-BICINCHONINATE
DISODIUM 2,2'-BIQUINOLINE-4,4'-DICARBOXYLATE
SODIUM BICINCHONINATE,4,4'-DICARBOXY-2,2'-BIQUINOLINE
2,2’-biquinoline-4,4’-dicarboxylicaciddisodiumsalt2h2o
SodiumBicinchoniate
SodiumBicinchoninate
2,2'-BIQUINOLINE-4,4'-DICARBOXYLIC ACID DISODIUM SALT 2-HYDRATE
4 4''-DICARBOXY-2 2''-BIQUINOLINE DISODIUM BCA
4,4'-Dicarboxy-2,2'-biquinoline disodium salt>98%
Bicinchoninic acid disodium salt, BCA disodium salt
4,4μ-Dicarboxy-2,2μ-biquinoline disodium salt, BCA, Disodium 2,2μ-biquinoline-4,4μ-dicarboxylate, 2,2μ-Biquinoline-4,4μ-dicarboxylic acid disodium salt
[EINECS(EC#)]

629-761-2
[Molecular Formula]

C20H11N2Na2O4
[MDL Number]

MFCD00037500
[Molecular Weight]

389.29
[MOL File]

979-88-4.mol
Chemical PropertiesBack Directory
[Melting point ]

300℃
[storage temp. ]

Inert atmosphere,2-8°C
[solubility ]

0.5% sodium bicarbonate: soluble50mg/mL
[form ]

Powder/Chunks
[color ]

white to light yellow
[Water Solubility ]

Soluble in water.
[Detection Methods]

HPLC
[Stability:]

Hygrscopic
[Major Application]

diagnostic assay manufacturing
hematology
histology
[InChI]

InChI=1S/C20H12N2O4.Na.H/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18;;/h1-10H,(H,23,24)(H,25,26);;
[InChIKey]

AUPXFICLXPLHBB-UHFFFAOYSA-L
[SMILES]

C(C1=CC(C2=NC3=CC=CC=C3C(C(=O)O)=C2)=NC2=CC=CC=C12)(=O)O.[NaH]
[CAS DataBase Reference]

979-88-4(CAS DataBase Reference)
[EPA Substance Registry System]

979-88-4(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
[Hazard Codes ]

Xn,Xi
[Risk Statements ]

R36/37:Irritating to eyes and respiratory system .
R42:May cause sensitization by inhalation.
R36/38:Irritating to eyes and skin .
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
[Safety Statements ]

S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[TSCA ]

Yes
[HS Code ]

29339900
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Irrit. 2
Skin Irrit. 2
Hazard InformationBack Directory
[Description]

2,2’-Biquinoline-4,4’-dicarboxylic acid (BCA) is a colorimetric reagent for the detection of copper (Cu+). BCA and Cu+ form a stable 2:1 complex that has an absorbance maximum at 562 nm. It is commonly used as a reagent in the colorimetric BCA protein quantitation assay in which Cu2+ is converted to Cu+ as a function of protein concentration under alkaline conditions.
[Chemical Properties]

White to light yellow powder
[Uses]

For determination of Cu and protein assays.Bicinchoninic acid disodium salt is useful for the determination of copper. It is also used for the determination of protein concentration.
[Application]

2,2'-Bicinchoninic Acid Disodium Salt is a photometric reagent for protein assay. It is used for determination of reducing sugar and protein via Cu(I). Also a specific reagent for Cu(I) with sensitivity similar to that of neocuproin.
[Biochem/physiol Actions]

Bicinchoninic acid is used for the determination of protein concentration. It is responsible for the making of intense purple complex with cuprous ion (Cu+), in presence of alkaline conditions. The amount of Cu+ is in relation with the protein concentration.
[References]

[1] P.K. SMITH. Measurement of protein using bicinchoninic acid[J]. Analytical biochemistry, 1985, 150 1: Pages 76-85. DOI: 10.1016/0003-2697(85)90442-7
[2] BRENNER A.J.  Harris E D. A Quantitative Test for Copper Using Bicinchoninic Acid[J]. Analytical biochemistry, 1995, 226 1: Pages 80-84. DOI: 10.1006/abio.1995.1194
[3] WALKER J M. The bicinchoninic acid (BCA) assay for protein quantitation.[J]. Methods in molecular biology, 1994, 32: 5-8. DOI: 10.1385/0-89603-268-x:5
Spectrum DetailBack Directory
[Spectrum Detail]

2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt(979-88-4)1HNMR
2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt(979-88-4)IR1
2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt(979-88-4)IR2
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

Bicinchoninic acid disodium salt(979-88-4)
[Sigma Aldrich]

979-88-4(sigmaaldrich)
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