| Identification | More | [Name]
4-Bromobenzenesulfonyl chloride | [CAS]
98-58-8 | [Synonyms]
4-BROMOBENZENESULFONYL CHLORIDE
4-BROMOBENZENESULPHONYL CHLORIDE
AKOS BBS-00004603
P-BROMOBENZENESULFONYL CHLORIDE
4-bromo-benzenesulfonylchlorid
Benzenesulfonylchloride,4-bromo-
Bromobenzenesulfonylchloride
4-BROMOBENZENESUNFONYL CHLORIDE
4-Bromobenzenesulfonyl chloride, 98+%
4-Bromo-Benzenesulfonyl
1-(4-BROMO-BENZENESULFONYL)-4-METHYLPIPERAZINE
4-bromobenzene-1-sulfonyl chloride
(4-Bromophenyl)chlorosulfone
4-Bromophenylsulfonyl chloride
p-Bromophenylsulfonyl chloride
p-Brosyl chloride
4-Bromobenzenesulfonic acid chloride
p-Bromobenzenesulfonic acid chloride
4-Bromobenzenesulfonylbromide | [EINECS(EC#)]
202-683-2 | [Molecular Formula]
C6H4BrClO2S | [MDL Number]
MFCD00007437 | [Molecular Weight]
255.52 | [MOL File]
98-58-8.mol |
| Chemical Properties | Back Directory | [Appearance]
white to beige crystals or crystalline powder | [Melting point ]
73-75 °C (lit.) | [Boiling point ]
153 °C/15 mmHg (lit.) | [density ]
1.7910 (estimate) | [Fp ]
152-154°C/26mm | [storage temp. ]
Refrigerator, Under Inert Atmosphere | [solubility ]
soluble in Chloroform, DMSO | [form ]
Crystals or Crystalline Powder | [color ]
White to beige | [Water Solubility ]
decomposes | [Sensitive ]
Moisture Sensitive | [Merck ]
14,1407 | [BRN ]
743518 | [InChI]
InChI=1S/C6H4BrClO2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H | [InChIKey]
KMMHZIBWCXYAAH-UHFFFAOYSA-N | [SMILES]
C1(S(Cl)(=O)=O)=CC=C(Br)C=C1 | [CAS DataBase Reference]
98-58-8(CAS DataBase Reference) | [EPA Substance Registry System]
Benzenesulfonyl chloride, 4-bromo- (98-58-8) |
| Questions And Answer | Back Directory | [Synthesis]
mixture of thiol (1 mmol), 30% H₂O₂ (3 mmol, 0.3 mL), and ZrCl₄ (1 mmol, 0.233 g) was stirred in MeCN (5 mL) at 25°C for an appropriate time. As shown by TLC, after the reaction was complete, the reaction mixture was quenched by adding H₂O (10 mL) and extracted with EtOAc (4 × 5 mL). The extract was dried with anhydrous MgSO₄, and the filtrate was evaporated under vacuum to give 4-bromobenzenesulfonyl chloride. |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS05 | [Signal word ]
Danger | [Hazard statements ]
H314 | [Precautionary statements ]
P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S27:Take off immediately all contaminated clothing . | [RIDADR ]
UN 3261 8/PG 2
| [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [REACH Registrations]
Active | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29049020 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Eye Dam. 1
Skin Corr. 1B |
| Hazard Information | Back Directory | [Chemical Properties]
white to beige crystals or crystalline powder | [Uses]
4-Bromobenzenesulfonyl chloride is used as activating agent in the synthesis of oligodeoxyribo- and oligoribo- nucleotides in solution. It also used in the synthesis of 4-(N-allylsulfamoyl)phenylboronic acid and in protection of amines as 4-bromobenzenesulfonamides. | [Uses]
4-Bromobenzenesulfonyl chloride is used for identification of amines, and also in the synthesis and inhibition studies of substituted N-L-histidinylphenylsulfonyl hydrazide.
| [Uses]
Identification of amines. | [Synthesis Reference(s)]
Synthesis, p. 1203, 1992 DOI: 10.1055/s-1992-26333 | [Purification Methods]
Wash the sulfonyl chloride with cold water, dry and recrystallise it from pet ether, or from ethyl ether cooled in powdered Dry-Ice after the ether solution had been washed with 10% NaOH until colourless, then dry it with anhydrous Na2SO4. Alternatively dissolve it in CHCl3, wash it with H2O, dry (Na2SO4), evaporate and recrystallise it. [Huntress & Carten J Am Chem Soc 62 511 1940.] Test for the SO2Cl group by dissolving it in EtOH and boiling with NH4CNS whereby a yellow amorphous precipitate forms on cooling. [Beilstein 11 IV 162.] |
|
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
|