ChemicalBook--->CAS DataBase List--->99420-15-2

99420-15-2

99420-15-2 Structure

99420-15-2 Structure
IdentificationBack Directory
[Name]

BTZO 1
[CAS]

99420-15-2
[Synonyms]

BTZO 1
BTZO-1 (BTZO 1)
2-Pyridin-2-yl-4H-1,3-benzothiazin-4-one
2-(2-Pyridinyl)-4H-1,3-benzothiazin-4-one
4H-1,3-Benzothiazin-4-one, 2-(2-pyridinyl)-
2-(Pyridin-2-yl)-4H-benzo[e][1,3]thiazin-4-one
[Molecular Formula]

C13H8N2OS
[MDL Number]

MFCD19690951
[MOL File]

99420-15-2.mol
[Molecular Weight]

240.28
Chemical PropertiesBack Directory
[Boiling point ]

454.9±37.0 °C(Predicted)
[density ]

1.35±0.1 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

DMSO: ≥7mg/mL
[form ]

powder
[pka]

-0.01±0.19(Predicted)
[color ]

white to tan
[InChI]

1S/C13H8N2OS/c16-12-9-5-1-2-7-11(9)17-13(15-12)10-6-3-4-8-14-10/h1-8H
[InChIKey]

GBAKVEWPYUIGHN-UHFFFAOYSA-N
[SMILES]

O=C1N=C(Sc2ccccc12)c3ccccn3
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

BTZO 1 is a binder of the macrophage migration inhibitory factor (MIF).
[Biological Activity]

BTZO-1 is a suppressor of cardiomyocyte apoptosis presumably by activation of antioxidant response element (ARE)-mediated gene expression. BTZO-1 binds to the macrophage migration inhibitory factor (MIF) th at is required to activate the glutathione S-transferase Ya subunit (GST Ya) gene ARE.
[storage]

Store at RT
Spectrum DetailBack Directory
[Spectrum Detail]

BTZO 1(99420-15-2)1HNMR
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