2316-26-9
2316-26-9 结构式
基本信息
3,4-二甲氧基肉桂酸
3,4-二甲氧基苯乙烯酸
3,4-二甲氧基苯丙烯酸
3,4-二甲氧基肉桂酸
3,4-二甲氧基苯乙烯酸, PREDOMINANTLY TRANS
3-(3,4-DIMETHOXYPHENYL)-2-PROPENOIC ACID
3-(3,4-DIMETHOXY-PHENYL)-ACRYLIC ACID
3',4'-DIMETHOXYCINNAMIC ACID
3,4-DIMETHOXYCINNAMIC ACID
AKOS BB/0042
AKOS BBS-00000090
AURORA 2809
DIMETHYLCAFFEIC ACID
(E)-3-(3,4-DIMETHOXYPHENYL)-2-PROPENOIC ACID
(E)-3-(3,4-DIMETHOXY-PHENYL)-ACRYLIC ACID
OTAVA-BB BB0107620014
RARECHEM BK HC T253
TIMTEC-BB SBB005722
(2E)-3-(3,4-Dimethoxyphenyl)-2-propenoic acid
2-Propenoic acid, 3-(3,4-dimethoxyphenyl)-
3-(3,4-dimethoxyphenyl)propenoicacid
3,4-Dimethoxyphenyl-2-propenoic acid
3,4-Di-O-methylcaffeic acid
Cinnamic acid, 3,4-dimethoxy-
物理化学性质
安全数据
制备方法
141-82-2
120-14-9
2316-26-9
通用方法：在干燥的反应容器中，将藜芦醛（500 mg，1.0当量）和丙二酸（981 mg，2.0当量）溶于二甲基甲酰胺（5 mL）中，随后加入DABCO（105 mg，0.2当量）。将反应混合物在100-110°C下搅拌反应60-90分钟。反应进程通过薄层色谱（TLC）监测。反应完成后，将混合物缓慢倒入冰水中，用乙酸乙酯（3×10 mL）萃取。合并有机相，用无水硫酸钠干燥，过滤并减压浓缩。粗产物通过从氯仿/己烷混合溶剂中重结晶纯化，得到3,4-二甲氧基肉桂酸，收率良好。
参考文献：
[1] Organic Letters, 2016, vol. 18, # 5, p. 1182 - 1185
[2] Oriental Journal of Chemistry, 2012, vol. 28, # 4, p. 1725 - 1728
[3] Asian Journal of Chemistry, 2017, vol. 29, # 7, p. 1561 - 1564
[4] Journal of Heterocyclic Chemistry, 1987, vol. 24, # 6, p. 1589 - 1594
[5] RSC Advances, 2015, vol. 5, # 34, p. 26596 - 26603
知名试剂公司产品信息
3,4-Dimethoxycinnamic acid, 99%(2316-26-9)
3,4-Dimethoxycinnamic acid, predominantly trans, 99%(2316-26-9)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | 11551 | 3,4-二甲氧基肉桂酸,主要为反式 3,4-Dimethoxycinnamic acid, 99%, predominantly trans isomer, Thermo Scientific Chemicals | 2316-26-9 | 5g | 265元 |
| 2025/05/22 | 11551 | 3,4-二甲氧基肉桂酸,主要为反式 3,4-Dimethoxycinnamic acid, 99%, predominantly trans isomer, Thermo Scientific Chemicals | 2316-26-9 | 25g | 690元 |
| 2025/05/22 | 11551 | 3,4-二甲氧基肉桂酸,主要为反式 3,4-Dimethoxycinnamic acid, 99%, predominantly trans isomer, Thermo Scientific Chemicals | 2316-26-9 | 100g | 2056元 |
常见问题列表
3,4-Dimethoxycinnamic acid (Methyl ferulic acid; 25, 50 and 100 µM) attenuates the ethanol-induced apoptosis of ethanolexposed L-02 cells.
3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) inhibits the expression levels of Nox4 and p22
phox
in L-02 cells.
3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) treatment attenuates ethanol-induced MAPK phosphorylation in L-02 cells.
3,4-Dimethoxycinnamic acid decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase, and downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner.