3211-76-5
3211-76-5 结构式
基本信息
硒代蛋氨酸
L-(+)-硒代蛋氨酸
(S)-(+)-2-氨基-4-(甲基硒)丁酸
L-(+)-2-AMINO-4-(METHYLSELENO)BUTANOIC ACID
L-(+)-SELENOMETHIONINE
L-SELENOMETHIONINE
(S)-(+)-2-AMINO-4-(METHYLSELENO)BUTANOIC ACID
(S)-2-AMINO-4-(METHYLSELENO)BUTYRIC ACID
SELENO-L-METHIONINE
SELENOMETHIONINE, L-(+)-
SEMET
L(+)-SELENOMETHIONINE 99+% E.E.
(S)-2-AMINO-4-(METHYLSELENYL)BUTYRIC ACID
L(+)-Selenomethionine, ee 99+%, 99+%
Butanoic acid, 2-amino-4-(methylseleno)-, (2S)-
L-SELENOMETHIONINE SELENO-L-METHIONINE L-SE-MET-OH
L-selenomethionine （L-se-Met-OH）
BUTYRICACID,2-AMINO-4-(METHYLSELENYL)-,L-
L-SELENOMETHIONINE 0.5%
L-SELENOMETHIONINE USP
THALLIUM ETHYLSUFATE
(S)-(+)-2-Amino-4-(methylseleno)butanoic acid, (S)-2-Amino-4-(methylseleno)butyric acid, L-Selenomethionine, Seleno-L-methionine
物理化学性质
安全数据
知名试剂公司产品信息
L(+)-Selenomethionine, ee 99+%, 99+%(3211-76-5)
L-Selenomethionine,>98.0%(T)(3211-76-5)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/01/25 | HY-B1000A | L-硒代蛋氨酸 L-SelenoMethionine | 3211-76-5 | 100mg | 550元 |
| 2024/01/25 | HY-B1000A | L-硒代蛋氨酸 L-SelenoMethionine | 3211-76-5 | 10mM * 1mLin Water | 605元 |
| 2024/01/25 | HY-B1000A | L-硒代蛋氨酸 L-SelenoMethionine | 3211-76-5 | 500mg | 1500元 |
常见问题列表
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Human Endogenous Metabolite
|
L-SelenoMethionine (1-500 μM; 24-72 h) is selectively inhibits the growth of prostate cancer cells, compared with normal cells.
L-SelenoMethionine (500 μM; 48 h) induce apoptosis in prostate cancer cells.
L-SelenoMethionine (500 μM; 48 h) causes an increase in arrest in the G2-M phase of the cell cycle selectively in prostate cancer cells.
L-SelenoMethionine (5 μM; 24 h) mitigates gene expression associated with the cellular stress response from 10 cGy irradiation.
Cell Viability Assay
| Cell Line: | Prostate cancer cells (LNCaP, PC-3, and DU145) and normal prostate cells (PrEC, PrSM, and PrSt) |
| Concentration: | 1, 5, 10, 50, 100, 500 μM |
| Incubation Time: | 24, 48, 72 hours |
| Result: | Inhibited the growth of prostate cancer cells, with a lower IC 50 (1-90 μM) at 72 h than normal prostate cells (>500 μM). |
Apoptosis Analysis
| Cell Line: | Prostate cancer cells (LNCaP, PC-3, and DU145) and normal prostate cells (PrEC, PrSM, and PrSt) |
| Concentration: | 500 μM |
| Incubation Time: | 48 hours |
| Result: |
Exhibited the highest level of DNA condensation in androgen-responsive LNCaP carcinoma cells, followed by PC-3 and DU145 cells.
Exhibited the nicked-end DNA labeling in prostate cancer cells. Promoted the PARP cleavage in prostate cancer cells. |
Cell Cycle Analysis
| Cell Line: | Prostate cancer cells (LNCaP, PC-3, and DU145) and normal prostate cells (PrEC, PrSM, and PrSt) |
| Concentration: | 500 μM |
| Incubation Time: | 48 hours |
| Result: |
Increased the sub-G0-G1 cell fraction of LNCaP (41.5%), PC-3 (12.1%), and DU145 cells (11.2%).
Caused a significant increases in G2 cells , particularly in LNCaP (13%), PC-3 (32%), and DU145 (20%) cells. |
RT-PCR
| Cell Line: | Human thyroid epithelial cells (HTori-3) |
| Concentration: | 5 μM |
| Incubation Time: | 24 hours |
| Result: | Downregulated the CDC6, GADD45A, FAS and ATF3 in irradiated cells. |
L-SelenoMethionine (0.06-12 μg/g diet; p.o. for 3 d) partially or completely prevent the decrease in the serum or plasma levels of total antioxidants in rats exposed to gamma rays, protons or HZE particles.