454-29-5
454-29-5 结构式
基本信息
DL-2-氨基-4-巯基丁酸
DL-类半胱氨酸
DL-巯基丁氨酸
DL-同型半胱氨酸
同型半胱氨酸
升半胱胺酸
2-氨基-4-巯基丁酸
2-AMINO-4-MERCAPTOBUYRIC ACID
DL-HOMOCYSTEINE
HOMOCYSTEINE, DL-
(+-)-homocysteine
dl-2-amino-4-mercaptobutyricacid
usafb-12
DL-Homocysteine 2-Amino-4-mercaptobuyric acid
2-amino-4-sulfanylbutanoic acid
HOMOCYSTEINE, DL-(RG)
TOTALHOMOCYSTEINE
H-DL-Hcys-OH
物理化学性质
安全数据
常见问题列表
DL-高半胱氨酸是多巴胺d2受体的变构拮抗剂。 L-高半胱氨酸（H591950）主要是天然存在的，可以再循环为蛋氨酸或转化为半胱氨酸。
| Target | Value |
|
KYNA
() | |
|
KAT
() |
DL-Homocysteine (0.1-0.5 mM) significantly enhances kynurenic acid (KYNA) production in rat cortical slices, and diministes the production of at 3.0, 5.0, and 10.0 mM, with the estimated IC 50 of 6.4 (5.5-7.5) mM. DL-Homocysteine dose-dependently inhibits kynurenine aminotransferases I (KATI) activity at concentrations ≥0.2 mM, with an IC 50 of 0.566 (0.442-0.724) mM, and the activity of KAT II with IC 50 value of 8.046 (5.804-11.154) mM.
DL-Homocysteine (1.3 mmol/kg, i.p.) increases KYNA content (pmol/g tissue) from 8.47 ± 1.57 to 13.04 ± 2.86 and 11.4 ± 1.72 in cortex, and from 4.11 ± 1.54 to 10.02 ± 3.08 in rat hippocampus.
知名试剂公司产品信息
DL-Homocysteine,>90.0%(T)(454-29-5)