55750-63-5
中文名称
6-(马来酰亚胺基)己酸琥珀酰亚胺酯
英文名称
N-Succinimidyl 6-maleimidohexanoate
CAS
55750-63-5
分子式
C14H16N2O6
MDL 编号
MFCD00043043
分子量
308.29
MOL 文件
55750-63-5.mol
更新日期
2024/04/22 17:23:41
55750-63-5 结构式
基本信息
中文别名
EMCS6-(马来酰亚胺基)己酸琥珀酰亚胺酯
英文别名
6-MALEIMIDOCAPROIC ACID N-SUCCINIMIDYL ESTEREMCS
EPSILON-MALEIMIDOCAPROIC ACID N-HYDROXYSUCCINIMIDE ESTER
N-(6-MALEIMIDOCAPROYLOXY)SUCCINIMIDE
N-(E-MALEIMIDOCAPROYLOXY)SUCCINIMIDE
N-(EPSILON-MALEIMIDOCAPROYLOXY)SUCCINIMIDE
N-[EPSILON-MALEIMIDOCAPROYLOXY]SUCCINIMIDE ESTER
N-SUCCINIMIDYL 6-MALEIMIDOCAPROATE
N-SUCCINIMIDYL 6-MALEIMIDOHEXANOATE
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
N-SUCCINIMIDYL-6-MALEMIDOCAPROATE, 99%
EPISILON-MALEIMIDOCAPROIC ACID N-*HYDROX YSUCCINIMID
6-maleimidohexanoic acid n-succinimidyl ester
N-(6-Maleimidocaproyloxy)succinimideN-Succinimidyl-6-maleimidohexanoate
6-Maleimidocaproic acid N-hydroxysuccinimide ester
N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent]
6-Maleimidocaproic acid N-succinimidyl ester, N-(ε-Maleimidocaproyloxy)succinimide, N-Succinimidyl 6-maleimidocaproate, EMCS
物理化学性质
熔点70-73 °C(lit.)
沸点480.6±47.0 °C(Predicted)
密度1.40±0.1 g/cm3(Predicted)
储存条件−20°C
溶解度chloroform: 100mg/mL
酸度系数(pKa)-2.21±0.20(Predicted)
形态powder
颜色灰白色至浅棕色
敏感性Light & Moisture Sensitive & Hygroscopic
BRN1499815
常见问题列表
简介
6-(马来酰亚胺基)己酸琥珀酰亚胺酯是一种异双官能团交联试剂，与胺和巯基反应性的延长间隔结合。通常，最初通过pH 7.5缓冲的酰胺键与含有初级胺的分子耦合(6.5-8.5)，第二次耦合是通过pH 6.8缓冲的硫醚键与含有游离巯基的分子耦合(6.5-7.0)。
应用
6-(马来酰亚胺基)己酸琥珀酰亚胺酯可用于酶免疫偶联剂和半抗原载体分子偶联剂的制备。包含9个原子链接器。与芳香族间隔物相比，延长的脂肪间隔物在耦合前稳定了马来酰亚胺。
生物活性
6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) 是一种异双官能团交联剂。EMCS 是一种制备半抗原结合物和酶免疫偶联物的独特而有用的试剂。靶点
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Non-cleavable
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体外研究
6-Maleimidohexanoic acid N-hydroxysuccinimide ester is coupled to the peptides, and then conjugated to the Adenovirus vector containing luciferase gene as adenovirus vector carrier.
6-(马来酰亚胺基)己酸琥珀酰亚胺酯价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/01/25 | HY-78961 | 6-(马来酰亚胺基)己酸琥珀酰亚胺酯 6-Maleimidohexanoic acid N-hydroxysuccinimide ester | 55750-63-5 | 50mg | 350元 |
| 2024/01/25 | HY-78961 | 6-(马来酰亚胺基)己酸琥珀酰亚胺酯 6-Maleimidohexanoic acid N-hydroxysuccinimide ester | 55750-63-5 | 100mg | 550元 |
| 2024/01/25 | HY-78961 | 6-(马来酰亚胺基)己酸琥珀酰亚胺酯 6-Maleimidohexanoic acid N-hydroxysuccinimide ester | 55750-63-5 | 500mg | 850元 |