6233-83-6
中文名称
醋酸缩宫素
英文名称
Oxytocin, monoacetate (salt)
CAS
6233-83-6
分子式
C2H4O2
分子量
60.052
MOL 文件
6233-83-6.mol
更新日期
2024/04/28 10:38:05
6233-83-6 结构式
基本信息
中文别名
醋酸缩宫素羟可待酮鉴别
羟可待酮鉴别 USP标准品
英文别名
Pitocin AcetateSynpitan Acetate
Uteracon Acetate
Orasthin Acetate
Perlacton Acetate
Syntocinon Acetate
50-56-6 (free base)
Oxytocin Monoacetate
α-Hypophamine acetate
Oxytocin Identification
所属类别
分析化学：药典标准品和杂质标准品物理化学性质
储存条件-20°C储存
溶解度DMSO:44.0(Max Conc. mg/mL);41.23(Max Conc. mM)
Water:50.0(Max Conc. mg/mL);46.85(Max Conc. mM)
Water:50.0(Max Conc. mg/mL);46.85(Max Conc. mM)
形态结晶固体
InChIKeyDSZOEVVLZMNAEH-SIVBSZNNNA-N
常见问题列表
生物活性
Oxytocin acetate 是一种多效的下丘脑肽 (hypothalamic peptide)，有助于分娩、哺乳和亲社会行为。Oxytocin acetate 可以作为一种压力应对分子，具有抗炎、抗氧化剂和保护作用，特别是在面对逆境或创伤时。体内研究
During the LMA task, rat core body temperature are modestly decreased. Oxytocin acetate (subcutaneous injection; 0.1 mg/kg-0.3 mg/kg; single dose) produces significantly greater hypothermia (at 0.3 mg/kg) than either saline or the two lower doses of oxytocin. Oxytocin at 0.3 mg/kg produces a significantly greater decrease in temperature than vehicle between 15-60 min post injection, whereas 0.1 mg/kg slightly decreases temperature at the 30 min time point only.Oxytocin acetate (0.1 mg/kg) engages in significantly more body sniffing and ano-genital sniffing compared with saline controls. It also increases the total time spent in social interaction (71.6±4.3 s), compared to those receiving vehicle (56.9±4.1 s).
| Animal Model: | Fifty-six male Lister-hooded rats (150–200 g) |
| Dosage: | 0.1 mg/kg-0.3 mg/kg |
| Administration: | Subcutaneous injection; 0.1 mg/kg-0.3 mg/kg; single dose |
| Result: | Produced significantly greater hypothermia (at 0.3 mg/kg) than the saline group. |