96020-91-6
96020-91-6 结构式
基本信息
盐酸依氟鸟氨酸一合水
依氟鸟氨酸盐酸盐一水物
盐酸依氟鸟氨酸一水合物
依氟鸟氨酸盐酸盐一水合物
依氟鸟氨酸盐酸盐一水合酸物
依氟鸟氨酸盐酸盐一水合物99%
2-二氟甲基-DL-鸟氨酸盐酸盐一水合物
2,5-二氨基-2-(二氟甲基)五烯酸盐酸盐水合物
Unii-4nh22ndw9h
DFMO EFLORNITHINE
Eflornithine HCl API
Eflornithine HCl hydrate
DMFO HCl/Eflornithine HCl
Eflornithine HCl Monohydrate
MDL-71782 hydrochloride hydrate
RMI-71782 hydrochloride hydrate
Eflornithine hydrochloride salt
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/01/25 | HY-B0744B | 依氟鸟氨酸盐酸盐一水合物 Eflornithine hydrochloride hydrate | 96020-91-6 | 100mg | 500元 |
| 2024/01/25 | HY-B0744B | 依氟鸟氨酸盐酸盐一水合物 Eflornithine hydrochloride hydrate | 96020-91-6 | 10mM * 1mLin Water | 550元 |
| 2024/01/25 | HY-B0744B | 依氟鸟氨酸盐酸盐一水合物 Eflornithine hydrochloride hydrate | 96020-91-6 | 500mg | 1500元 |
常见问题列表
| Target | Value |
| Orn decarboxylase |
用α-difluoromethyl-Orn处理BY2细胞，抑制其过氧化氢的产生，但并没有发生程序性细胞死亡。
Eflornithine is the only new molecule registered for the treatment of human African trypanosomiasis over the last 50 years. It is the drug used mainly as a back-up for melarsoprol refractory Trypanosoma brucei gambiense cases. In subjects with excessive, unwanted facial hair, eflornithine 15% cream is superior to placebo in reducing hair growth. After 24 weeks' treatment, 58% of eflornithine and 34% of placebo subjects have at least some improvement in facial hirsutism. The hair growth inhibitory activity of eflornithine is significantly enhanced when the eflornithine cream is applied onto a mouse skin area pretreated with microneedles. Treatment of coarctation hypertensive rats with eflornithine results in a normalization of the contractile intensity to KCI and norepinephrine and relaxations to acetylcholine by 14 days of hypertension.