976-71-6

基本信息
刊利酮
卡利酮
烯睾丙内酯
坎利酮-D4
螺内酯相关物质A
安体舒通EP杂质F
依普利酮CANRENONE杂质
6-去氢睾(甾)酮-17α-丙酸-γ-内酯
雄甾-4,6-二烯-17β-醇-3-酮-17α-丙酸内酯
11614r.p
phanurane
CANRENONE
ALDADIENE
NSC 261713
CANRENONE-D4
Canrenone, >=97%
Canrenone98.5%Min
spirolactonesc14266
物理化学性质
制备方法
报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
2025/02/08 | HY-B1438 | 坎利酮 Canrenone | 976-71-6 | 50mg | 500元 |
2025/02/08 | HY-B1438 | 坎利酮 Canrenone | 976-71-6 | 10mM * 1mLin DMSO | 550元 |
2025/02/08 | HY-B1438 | 坎利酮 Canrenone | 976-71-6 | 100 mg | 800元 |
常见问题列表
Human Endogenous Metabolite
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Canrenone inhibits the production of eortieosterone, 18-hydroxydesoxyeortieosterone, 18-hydroxycorticosterone and aldosterone in a dose-dependent manner. Canrenone dose-dependently reduces platelet-derived growth factor–induced cell proliferation and motility. Canrenone inhibits the activity of the Na + /H + exchanger 1 induced by platelet-derived growth factor.
Canrenone is the principal active metabolite of Spironolactone in the rat only for a limited period. During chronic treatment a difference developed between the effect of Spironolactone and Canrenone on the RAAS indicating a decrease in the anti-mineralocorticoid activity of Canrenone and an increase in the efficacy of Spironolactone.