PF-02341272
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- CAS号:
- 168828-58-8
- 英文名:
- PNU 100480
- 英文别名:
- CS-2604;U-100480;Sutezolid;PNU 100480;PF-02341272;Sutezolid 13C4;Sutezolid (PNU-100480);Sutezolid >=98% (HPLC);PNU-100480; U-100480; PF-02341272;Sutezolid (PNU-100480, PF-02341272)
- 中文名:
- PF-02341272
- 中文别名:
- 化合物SUTEZOLID;(S)-N-[[3-(3-氟-4-硫代吗啉基苯基)-2-氧代噁唑烷-5-基]甲基]乙酰胺;(S)-N-((3-(3-氟-4-硫代吗啉代苯基)-2-氧亚基噁唑烷-5-基)甲基)醋胺石;N-[[(5S)-3-[3-氟-4-(4-硫代吗啉基)苯基]-2-氧代-5-恶唑烷基]甲基]乙酰胺
- CBNumber:
- CB32628274
- 分子式:
- C16H20FN3O3S
- 分子量:
- 353.41
- MOL File:
- 168828-58-8.mol
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PF-02341272化学性质
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熔点:
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186-187°C
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沸点:
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609.0±55.0 °C(Predicted)
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密度:
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1.321±0.06 g/cm3(Predicted)
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储存条件:
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room temp
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溶解度:
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DMSO: soluble20mg/mL, clear
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形态:
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powder
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酸度系数(pKa):
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15.53±0.46(Predicted)
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颜色:
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white to beige
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旋光性 (optical activity):
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[α]/D -8 to -12°, c = 1 in chloroform-d
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PF-02341272性质、用途与生产工艺
Sutezolid (PNU-100480) 是一种具有口服活性恶唑烷酮抗菌剂，通过抑制细菌蛋白质合成发挥作用。Sutezolid 具有较强的抗分枝杆菌活性，用于耐药结核病的研究。
Sutezolid (PNU-100480) exhibits excellent in vitro activity against multiple clinical isolates of
Mycobacterium avium
complex (MIC’s=0.5-4 µg/mL).
Sutezolid (PNU-100480) is a thiomorpholinyl analog of linezolid with superior efficacy against
M. tuberculosis
in the hollow-fiber, mouse, and whole-blood models.
PF-02341272
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-10392 | PF-02341272
Sutezolid | 168828-58-8 | 5mg | 700元 |
| 2024/01/25 | HY-10392 | PF-02341272
Sutezolid | 168828-58-8 | 10mM * 1mLin DMSO | 770元 |
168828-58-8, PF-02341272 相关搜索:
- (S)-N-[[3-(3-氟-4-硫代吗啉基苯基)-2-氧代噁唑烷-5-基]甲基]乙酰胺
- (S)-N-((3-(3-氟-4-硫代吗啉代苯基)-2-氧亚基噁唑烷-5-基)甲基)醋胺石
- 化合物SUTEZOLID
- N-[[(5S)-3-[3-氟-4-(4-硫代吗啉基)苯基]-2-氧代-5-恶唑烷基]甲基]乙酰胺
- 168828-58-8
- N-({(5S)-3-[3-Fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-1,3- oxazolidin-5-yl}methyl)acetamide
- U 100480,oxazolidinone,Antibiotic,protein,Sutezolid,synthesis,Bacterial,Inhibitor,PF 02341272,inhibit,PF02341272,U100480,antimicrobial,tuberculosis,PNU 100480,PNU100480
- Sutezolid 13C4
- N-[[(5S)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
- Sutezolid >=98% (HPLC)
- Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-
- Sutezolid (PNU-100480)
- CS-2604
- PNU 100480 - PF 02341272 | U 100480 | Sutezolid
- U-100480
- PNU-100480; U-100480; PF-02341272
- Sutezolid (PNU-100480, PF-02341272)
- PF-02341272
- (S)-N-((3-(3-fluoro-4-thiomorpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide(WXC06631)
- (S)-N-((3-(3-fluoro-4-thiomorpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide
- Sutezolid
- (S)-N-[[3-[3-Fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-acetamide
- PNU 100480