依诺他滨
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- CAS号:
- 55726-47-1
- 英文名:
- Enocitabine
- 英文别名:
- BH-AC;CS-1807;SUNRABIN;NSC-239336;ENOCITABINE;Enocitabine API;BEHENOYLCYTOSINE ARABINOSIDE;N4-Behenoylcytosine arabinoside;n(sup4)-behenoylcytosinearabinoside;ENOCITABINE 98.5+% ANTINEOPLASTIC DRUGS
- 中文名:
- 依诺他滨
- 中文别名:
- 依诺他滨;依诺他宾;山嵛阿糖啶;山嵛阿糖嘧啶;化合物 T15235;N-[1-[3,4-二羟基-5-(羟甲基)氧杂环戊-2-基]-2-氧代嘧啶-4-基]山嵛酸酰胺;N-(1-((2R,3S,4S,5R)-3,4-二羟基-5-(羟甲基)四氢呋喃-2-基)-2-氧代-1,2-二氢嘧啶-4-基)二十二酰胺
- CBNumber:
- CB3266605
- 分子式:
- C31H55N3O6
- 分子量:
- 565.78
- MOL File:
- 55726-47-1.mol
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依诺他滨化学性质
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熔点:
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141-142°C
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比旋光度:
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D +70° (c = 1 in THF, 22°)
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沸点:
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630.87°C (rough estimate)
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密度:
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1.0967 (rough estimate)
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折射率:
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1.7800 (estimate)
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储存条件:
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Keep in dark place,Sealed in dry,Store in freezer, under -20°C
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溶解度:
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DMSO (Slightly, Heated), Methanol (Slightly, Heated), THF (Slightly, Heated, Soncited)
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酸度系数(pKa):
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10.14±0.20(Predicted)
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形态:
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Solid
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颜色:
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White to Off-White
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CAS 数据库:
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55726-47-1(CAS DataBase Reference)
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依诺他滨性质、用途与生产工艺
Enocitabine 是一种核苷类似物，是一种有效的 DNA 复制抑制剂和 DNA链终止剂。Enocitabine 抑制人巨细胞病毒的复制，具有抗白血病和抗病毒活性。
Enocitabine is resistant to deamination because Enocitabine bears a highly lipophilic group at the 4-amino position of the cytosine moiety of cytarabine.
The combined effects of Pirarubicin and Enocitabine on HeLa S3 human uterine cervix carcinoma and K562 human myelocytic leukemia cells are determined by enhancement of their cytotoxic activities. Enocitabine or etoposide shows synergistic effects on HeLa S3 and K562 cells.
In the presence of Enocitabine, triphosphate forms of the nucleoside analogs are detected in the human cytomegalovirus (HCMV)-infected cells, and synthesis of HCMV DNA is strongly suppressed.
依诺他滨
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/25 | HY-123523 | Enocitabine | | 1 mg | 1523元 |
| 2024/01/25 | HY-123523 | 依诺他滨
Enocitabine | 55726-47-1 | 5mg | 4000元 |
依诺他滨
生产厂家
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依诺他滨国内生产厂家
55726-47-1, 依诺他滨 相关搜索:
- Pharmaceuticals
- Intermediates & Fine Chemicals
- 标准品
- 医药中间体
- C31H55N3O6
- 化合物 T15235
- N-(1-((2R,3S,4S,5R)-3,4-二羟基-5-(羟甲基)四氢呋喃-2-基)-2-氧代-1,2-二氢嘧啶-4-基)二十二酰胺
- 依诺他宾
- 山嵛阿糖嘧啶
- 山嵛阿糖啶
- 依诺他滨
- N-[1-[3,4-二羟基-5-(羟甲基)氧杂环戊-2-基]-2-氧代嘧啶-4-基]山嵛酸酰胺
- 55726-47-1
- Inhibitor,CMV,Enocitabine,inhibit,DNA/RNA Synthesis,Sunrabin,Cytomegalovirus,AML,acute myelogenous leukaemia,Nucleoside Antimetabolite/Analog
- N-(1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)docosanamide
- N(4)-behenoyl-1-beta-arabinofuranosylcytosine
- 1-benzimidazolyl-(5-bromo-2-furanyl)methanone
- CS-1807
- N-[1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]docosanamide Enocitabine
- ENOCITABINE 98.5+% ANTINEOPLASTIC DRUGS
- N-[1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]docosanamide
- N4-Behenoylcytosine arabinoside
- N4-Behenoyl-1-β-D-arabinofuranosylcytosine
- Docosanamide, N-(1-β-D-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-
- N-(1-B-D-Arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)docosanamide, Behenoylcytosine Arabinoside, BH-AC, NSC-239336, Sunrabin
- Enocitabine API
- 1-β-D-Arabinofuranosyl-4-(1-oxodocosyl)amino-1,2-dihydropyrimidin-2-one
- N-[1-[(2R,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxo-pyrimidin-4-yl]docosanamide
- n(sup4)-behenoylcytosinearabinoside
- n(sup4)-behenoyl-1-beta-d-arabinofuranosylcytosine
- n-(1-beta-d-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-docosanamid
- ENOCITABINE
- BH-AC
- BEHENOYLCYTOSINE ARABINOSIDE
- SUNRABIN
- NSC-239336
- N-(1-BETA-D-ARABINOFURANOSYL-1,2-DIHYDRO-2-OXO-4-PYRIMIDINYL)DOCOSANAMIDE