9,10-二羟基十八酸
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- CAS号:
- 120-87-6
- 英文名:
- 9,10-DIHYDROXYSTEARIC ACID
- 英文别名:
- AKOS 236-72;9,10-Dihydroxystearate;60154-91-8 (Lithium salt);84753-04-8 (Ammonium salt);9,10-DIHYDROXYSTEARIC ACID;37734-46-6 (Potassium salt);84682-00-8 (Magnesium salt);74220-13-6 (Di-calcium salt);20731-55-9 (Hydrochloride salt);9 10-DIHYDROXYOCTADECANOIC ACID
- 中文名:
- 9,10-二羟基十八酸
- 中文别名:
- 二羟基硬脂酸;9,10-二羥硬脂酸;9,10-二羥十八酸;9,10-二羟硬脂酸;9,10-二羟基硬脂酸;9,10-二羟基十八酸;9,10-二羟基十八烷酸;9,10-双羟基十八烷酸
- CBNumber:
- CB5366507
- 分子式:
- C18H36O4
- 分子量:
- 316.48
- MOL File:
- 120-87-6.mol
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9,10-二羟基十八酸化学性质
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熔点:
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90°C
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沸点:
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375.89°C (rough estimate)
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密度:
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0.9730 (rough estimate)
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折射率:
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1.4434 (estimate)
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溶解度:
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DMF: 25mg/mL; DMSO: 10mg/mL; DMSO:PBS (pH 7.2) (1:5): 0.16mg/mL; Ethanol: 5mg/mL
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形态:
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A crystalline solid
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酸度系数(pKa):
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4.78±0.10(Predicted)
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9,10-二羟基十八酸性质、用途与生产工艺
9,10-Dihydroxystearic acid 是油酸的氧化产物，可以改善 KKAy 小鼠的葡萄糖耐量和胰岛素敏感性。
5-20 μmol/L 9,10-Dihydroxystearic acid (DHSA) does not activate PPAR-γ in CV-1 cells but 50-100 μmol/L DHSA activates PPAR-γ in a dose-dependent way. 9,10-Dihydroxystearic acid does not activate PPAR-α in CV-1 cells.
9,10-Dihydroxystearic acid (DHSA; fed with high fat diet containing 4% DHSA; for 5-6 weeks) treatment improves glucose tolerance and insulin sensitivity in KKAy mice.
9,10-二羟基十八酸
上下游产品信息
上游原料
下游产品
120-87-6, 9,10-二羟基十八酸 相关搜索:
- C18H36O4
- C17H33OH2COOH
- 9,10-二羟基十八烷酸
- 9,10-二羟硬脂酸
- 二羟基硬脂酸
- 9,10-二羥硬脂酸
- 9,10-二羥十八酸
- 9,10-双羟基十八烷酸
- 9,10-二羟基硬脂酸
- 9,10-二羟基十八酸
- 120-87-6
- Octadecanoic acid,9,10-dihydroxy
- 9,10-Dihydroxystearate
- 84753-04-8 (Ammonium salt)
- 84682-00-8 (Magnesium salt)
- 74220-13-6 (Di-calcium salt)
- 60154-91-8 (Lithium salt)
- 37734-46-6 (Potassium salt)
- 20731-55-9 (Hydrochloride salt)
- 9,10-DIHYDROXYSTEARIC ACID
- 9 10-DIHYDROXYOCTADECANOIC ACID
- AKOS 236-72