硫酸依色林
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- CAS号:
- 64-47-1
- 英文名:
- ESERINE SULFATE
- 英文别名:
- eserinesulphate;ESERINE SULFATE;physostigmineso4;Physostigminsulfat;Eserine Impurity 1;ESERINE HEMISULFATE;PHYSOSTIGMINE SULFATE;physostigminesulphate;PHYSOSOTIGMINESULPHATE;ESERINE HEMISULFATE SALT
- 中文名:
- 硫酸依色林
- 中文别名:
- 硫酸依色林;硫酸毒豆碱;依色林硫酸盐;硫酸毒扁豆盐;扁豆半硫酸盐;毒扁豆碱硫酸盐;毒扁豆碱杂质1;伊色林 半硫酸盐;毒扁豆碱 半硫酸盐;化合物 T23153
- CBNumber:
- CB6269177
- 分子式:
- C30H44N6O8S
- 分子量:
- 648.77
- MOL File:
- 64-47-1.mol
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硫酸依色林性质、用途与生产工艺
Physostigmine hemisulfate (Eserine hemisulfate) 是一种可逆的乙酰胆碱酯酶 (AChE) 抑制剂。Physostigmine hemisulfate 可以透过血脑屏障并刺激中枢胆碱能神经传递。Physostigmine hemisulfate 能逆转阿尔茨海默病转基因小鼠的记忆缺陷。Physostigmine hemisulfate 也是抗胆碱能中毒的解毒剂。
Physostigmine hemisulfate (Eserine hemisulfate; 0.03-0.3 mg/kg; s.c.; daily for 6 weeks) improves deficits in contextual and cued memory in Tg(+) mice.
Physostigmine hemisulfate (IV; 0.1, 0.2 mg/kg) delays time to emergence from isoflurane anesthesia at doses ≥0.2 mg/kg in male Sprague-Dawley rats.
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Animal Model:
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Heterozygous transgenic mice (Tg(+) mice)
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Dosage:
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0.03, 0.1, and 0.3 mg/kg
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Administration:
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SC; daily for 6 weeks
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Result:
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Tended to normalize the contextual memory deficit in Tg(+) animals so that they became more similar to Tg(-) animals.
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硫酸依色林
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64-47-1, 硫酸依色林 相关搜索:
- Acetylcholine receptor
- C15H21N3O212H2SO4
- C15H21N3O205H2SO4
- C30H44N6O8S
- C15H21N3O22H2SO4
- 毒扁豆碱杂质1
- 化合物 T23153
- 伊色林 半硫酸盐
- 依色林硫酸盐
- 毒扁豆碱 半硫酸盐
- 硫酸毒扁豆盐
- 扁豆半硫酸盐
- 毒扁豆碱硫酸盐
- 硫酸依色林
- 硫酸毒豆碱
- 64-47-1
- Eserine Impurity 1
- Eserine hemisulfate saltQ: What is
Eserine hemisulfate salt Q: What is the CAS Number of
Eserine hemisulfate salt Q: What is the storage condition of
Eserine hemisulfate salt Q: What are the applications of
Eserine hemisulfate salt
- (3AS)-CIS-1,2,3,3A,8,8A-HEXAHYDRO-1,3A,8-TRIMETHYLPYRROLO[2,3-B]INDOL-5-OL METHYLCARBAMATE HEMISULFATE
- ESERINE HEMISULFATE SALT
- ESERINE HEMISULFATE
- ESERINE SULFATE
- physostigminesulphate
- physostigmineso4
- eserinesulphate
- (3aS-cis)-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol methylcarbamate hemisulfate
- Physostigminsulfat
- PHYSOSOTIGMINESULPHATE
- Pyrrolo2,3-bindol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, methylcarbamate (ester), (3aS,8aR)-, sulfate (2:1) (salt)
- PHYSOSTIGMINE SULFATE
- PHYSOSTIGMINE HEMISULFATE SALT
- PHYSOSTIGMINE HEMISULFATE
- 3-b)indole,1,2,3,3a,8,8a-hexahydro-5-hydroxy-1,3a,8-trimethyl-pyrrolo(meth
- (3as-cis)-ylcarbamate(estersulfate(2:1)
- (3as-cis)-amate(estersulfate(2:1)(salt)