氟立班丝氨可以适度提高性功能（与安慰剂相比高10%）主要在绝经前女性伴性欲障碍（HSDD）中比较，她们对性的兴趣严重降低。对男性而言，氟立班丝氨是不同于西地那非（威尔刚），西地那非是在有需要前（性行为之前）服用而且是通过增加血液流向阴茎来产生药效。氟立班丝氨必须每日服用而且它是作用于大脑调控性的区域。氟立班丝氨有严重的潜在副作用，包括血压非常低、晕倒、恶心等。如果女性有摄入酒精或服用避孕药物，那么这些风险会增加及变得更严重。
氟立班丝氨显示其对5-HT1A与5-HT2受体具有亲和力，因此还是对治疗多种疾病是有希望的治疗剂，例如抑郁症、精神分裂症、帕金森氏症、焦虑症、睡眠障碍、性及精神异常以及与年龄相关的记忆障碍。
The multifunctional serotonergic agent Flibanserin is both a serotonin 1A agonist and a serotonin 2A antagonist. Flibanserin theoretically improves sexual functioning by enhancing downstream release of dopamine and norepinephrine while reducing serotonin release in the brain circuits that mediate symptoms of reduced sexual interest and desire. Flibanserin, a new molecular entity for the treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women. Flibanserin improves interest in and desire for sex by hypothetically targeting these circuits and causing the release of dopamine and norepinephrine while also reducing the release of serotonin. Flibanserin has demonstrated clinical efficacy in premenopausal women who have reduced interest in and desire for sex and has 2 principal pharmacologic actions in microcircuits: it is a full agonist at postsynaptic serotonin 5HT1A receptors and an antagonist at postsynaptic 5HT2A receptors.