N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt
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- CAS-Nr.
- 150374-95-1
- Englisch Name:
- N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt
- Synonyma:
- ONO5046-Na;EI546 sodium;LY544349 sodium;SIVELESTAT SODIUM;Sodium sivelestat;Sivelestat sodium sa;Sivelestat sodium salt;Sivelestat SodiuM anhydrous;N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycinesodiumsalt;sodium,2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate
- CBNumber:
- CB02131171
- Summenformel:
- C20H21N2NaO7S
- Molgewicht:
- 456.44
- MOL-Datei:
- 150374-95-1.mol
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N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt Eigenschaften
- Schmelzpunkt:
- 104-108 °C(Solv: water (7732-18-5))
- storage temp.
- Desiccate at RT
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
Sicherheit
N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Treatment of acute lung injury; acute respiratory distress syndrome (elastase inhibitor).
Biologische Aktivität
Selective leukocyte elastase inhibitor (IC 50 = 44 nM) that displays no activity at a range of other proteases. Inhibits NF- κ B activation and LTB 4 -induced neutrophil transmigration in vitro . Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo .
N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 73)Lieferanten
150374-95-1()Verwandte Suche:
- n-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(s)-glycine monosodium salt
- SIVELESTAT SODIUM
- N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycinesodiumsalt
- Sivelestat sodium salt
- Glycine, N-[2-[[[4-(2,2-diMethyl-1-oxopropoxy)phenyl]sulfonyl]aMino]benzoyl]-, MonosodiuM salt
- Sivelestat SodiuM anhydrous
- sodium,2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate
- sodium 2-[[[2-[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonylamino]phenyl]-oxomethyl]amino]acetate
- N-[2-[[[4-(2,2-Dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycine monosodium salt USP/EP/BP
- Sivelestat sodium sa
- EI546 sodium
- LY544349 sodium
- ONO5046-Na
- Sodium sivelestat
- 150374-95-1
- GYL
