Tegaserod

Tegaserod Struktur
145158-71-0
CAS-Nr.
145158-71-0
Englisch Name:
Tegaserod
Synonyma:
TEGASEROD;Tegaserode;Tegaserod USP/EP/BP;2-[(5-methoxy-1h-indol-3-yl)methylene]-n-pentylhydrazine-carboximidamide;Hydrazinecarboximidamide, 2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pentyl-;(E)-2-((5-methoxy-1H-indol-3-yl)methylene)-N-pentylhydrazine-1-carboximidamide;Tegaserod D10Q: What is Tegaserod D10 Q: What is the CAS Number of Tegaserod D10;Tegaserod 13CD3Q: What is Tegaserod 13CD3 Q: What is the CAS Number of Tegaserod 13CD3;Tegaserod D11 (Major-D10)Q: What is Tegaserod D11 (Major-D10) Q: What is the CAS Number of Tegaserod D11 (Major-D10)
CBNumber:
CB0225423
Summenformel:
C16H23N5O
Molgewicht:
301.39
MOL-Datei:
145158-71-0.mol

Tegaserod Eigenschaften

Schmelzpunkt:
155°
Siedepunkt:
470.6±48.0 °C(Predicted)
Dichte
1.18
storage temp. 
2-8°C
pka
15.81±0.30(Predicted)
CAS Datenbank
145158-71-0(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher Xi
R-Sätze: 20/21/22-36/37/38
S-Sätze: 36/37-36-26

Tegaserod Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Verwenden

Treatment of gastrointestinal motility disorders (selective serotonin 5HT4antagonist).

Indications

Tegaserod (Zelnorm) is serotonin-4 (5-HT4) receptor agonists that stimulate GI motility.

Clinical Use

Tegaserod is being developed as a treatment for constipation- predominant irritable bowel syndrome (IBS). Within the first week, patients treated with tegaserod had significant improvements in abdominal pain and discomfort, constipation, and overall well-being. Efficacy was maintained throughout the treatment period. Tegaserod also demonstrated significant improvements in the three bowel-related assessments (stool frequency, stool consistency, and straining) within the first week, and these improvements were sustained throughout the treatment period. The most common adverse events reported thus far are headache and diarrhea.

Tegaserod Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Tegaserod Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 70)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29914 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873
sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49390 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569265 +86-18612256290
1056@dideu.com China 3581 58
Hubei Ipure Biology Co., Ltd
+8613367258412
ada@ipurechemical.com China 10326 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167
1026@dideu.com China 9320 58
AFINE CHEMICALS LIMITED
0571-85134551
info@afinechem.com CHINA 15377 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 992 58
changzhou huayang technology co., ltd
+8615250961469
2571773637@qq.com China 9821 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418684 +8618949823763
sales@tnjchem.com China 25363 58

145158-71-0()Verwandte Suche:


  • TEGASEROD
  • 2-[(5-methoxy-1h-indol-3-yl)methylene]-n-pentylhydrazine-carboximidamide
  • Tegaserode
  • Tegaserod D11 (Major-D10)Q: What is Tegaserod D11 (Major-D10) Q: What is the CAS Number of Tegaserod D11 (Major-D10)
  • Tegaserod D10Q: What is Tegaserod D10 Q: What is the CAS Number of Tegaserod D10
  • Tegaserod 13CD3Q: What is Tegaserod 13CD3 Q: What is the CAS Number of Tegaserod 13CD3
  • Tegaserod USP/EP/BP
  • Hydrazinecarboximidamide, 2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pentyl-
  • (E)-2-((5-methoxy-1H-indol-3-yl)methylene)-N-pentylhydrazine-1-carboximidamide
  • 145158-71-0
  • C16H23N5O
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