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Methylenblau (C.I. 52015) Produkt Beschreibung

Methylene Blue Struktur
61-73-4
CAS-Nr.
61-73-4
Bezeichnung:
Methylenblau (C.I. 52015)
Englisch Name:
Methylene Blue
Synonyma:
CI 52015;S NO 1038;SWISS BLUE;Chromosmon;Nsc 617593;D&CBLUENO.1;CI NO 52015;BASIC BLUE 9;Schultz 1038;Urolene Blue
CBNumber:
CB2748858
Summenformel:
C16H18ClN3S
Molgewicht:
319.85
MOL-Datei:
61-73-4.mol

Methylenblau (C.I. 52015) Eigenschaften

Schmelzpunkt:
190 °C (dec.)(lit.)
Dichte
1.0 g/mL at 20 °C
Brechungsindex
n20/D1.347
Flammpunkt:
45 °C
storage temp. 
Store at RT
Löslichkeit
Soluble in water, ethanol, ethylene glycol, methyl cellosolve
Aggregatzustand
Liquid
pka
2.6, 11.2(at 25℃)
Colour Index 
52015
Farbe
Green
Wichte
0.98
Wasserlöslichkeit
40 g/L (20 ºC)
maximale Wellenlänge (λmax)
661 nm
Merck 
14,6060
BRN 
3641570
Biologische Anwendungen
Detecting microorganisms; treating diabetic retinopathy,macular degeneration,malignant uveal melanomas,erysipelas,hidradenitis suppurativa,inflammation,skin diseases
NIST chemische Informationen
Methylene blue(61-73-4)
EPA chemische Informationen
Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride(61-73-4)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xn
R-Sätze: 10-41-22-20/21/22-36/37/38
S-Sätze: 26-39-36
RIDADR  UN 1993 3/PG 3
WGK Germany  3
RTECS-Nr. SP5740000
HS Code  32049010
Giftige Stoffe Daten 61-73-4(Hazardous Substances Data)
Toxizität LD50 oral in rat: 1180mg/kg
Bildanzeige (GHS)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H226 Flüssigkeit und Dampf entzündbar. Entzündbare Flüssigkeiten Kategorie 3 Warnung
Sicherheit
P370+P378 Bei Brand: zum Löschen verwenden.
P403+P235 An einem gut belüfteten Ort aufbewahren. Kühl halten.

Methylenblau (C.I. 52015) Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R10:Entzündlich.
R41:Gefahr ernster Augenschäden.
R22:Gesundheitsschädlich beim Verschlucken.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

green fine crystalline powder

Verwenden

A useful inhibitor of cGMP-mediated processes and a useful stain

Definition

ChEBI: An organic chloride salt having 3,7-bis(dimethylamino)phenothiazin-5-ium as the counterion. A commonly used dye that also exhibits antioxidant, antimalarial, antidepressant and cardioprotective properties.

Hazard

Toxic by ingestion.

Biologische Aktivität

Biological stain and redox indicator. Inhibits tau filament formation (IC 50 = 1.9 μ M). Also inhibits soluble guanylyl cyclase.

Clinical Use

Methylene blue is 3,7-bis(dimethylamino)-phenazathioniumchloride (Urised). The compound occurs as a dark greencrystalline powder with a metallic appearance that is solublein water (1:25) and alcohol (1:65).
Methylene blue has weak antiseptic properties that makeit useful for the treatment of cystitis and urethritis. The actionof methylene blue is considered to be bacteriostatic.The compound colors the urine and stool blue green.

Veterinary Drugs and Treatments

Methylene blue is used primarily for treating methemoglobinemia secondary to oxidative agents (nitrates, chlorates) in ruminants. It is also employed occasionally as adjunctive or alternative therapy for cyanide toxicity.
Intra-operative methylene blue is also being used to preferentially stain islet-cell tumors of the pancreas in dogs in order to aid in their surgical removal or in determining the animal’s prognosis.

läuterung methode

Crystallise the chloride from 0.1M 664 2HCl (16mL/g), the crystals are separated by centrifugation, washed with chilled EtOH and diethyl ether, and dried under vacuum. Crystallise it from 50% aqueous EtOH, wash it with absolute EtOH, and dry it at 50-55o for 24hours. It has also been crystallised from *benzene/MeOH (3:1). It has been salted out with NaCl from a commercial concentrated aqueous solution, then crystallised from water, and dried at 100o in an oven for 8-10hours. [Beilstein 27 III/IV 5152.]

Methylenblau (C.I. 52015) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Methylenblau (C.I. 52015) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 177)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21671 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32447 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1861 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8918 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6372 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 sales@guangaobio.com CHINA 23049 58
Shandong chuangyingchemical Co., Ltd.
13156170209
sale@chuangyingchem.com CHINA 4405 58

61-73-4(Methylenblau (C.I. 52015))Verwandte Suche:


  • METHYLENE BLUE SOLUTION, 0.5% IN WATER
  • METHYLENE BLUE SOLUTION ALKALINE ACC. TO LOEFFLER
  • METHYLENE BLUE SOLUTION ACCORDING TO LOE FFLER FOR MICROSCOPY
  • METHYLENE BLUE CERTIFIED (C.I. 52015) FOR STAINING AND REAGENT FOR SPECTROSCOPY USE
  • METHYLENE BLUE INDICATOR, HIGH PURITY BIOGICAL STAIN, SPECTROPHOTOMETRIC ANALYSIS & MICROBIOLOGY GRADE 98.5%, C.I.NO 52015
  • METHYLENE BLUE POLYCHROME
  • METHYLENE BLUE POLYCHROME (MCFADYEN'S) 1% AQUEOUS STAINING SOLUTION
  • METHYLENE BLUE TABLETS FOR MILK TESTING
  • METHYLENE BLUE TECHNICAL GRADE C.I. 52015
  • METHYLENE BLUE TRIHYDRATE HIGH PURITY BIOLOGICAL STAIN
  • METHYLENE BLUE, 1% W V AQUEOUS SOLUTION
  • METHYLENE BLUE, 100X DNA STAIN ULTRA PURE GRADE
  • MethyleneBlueGr
  • Basicblue9=Methyleneblue
  • METHYLENE BLUE 3 H2O
  • Methylene Blue, certified, pure
  • Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride
  • lǒffler's alkaline methylene blue stain solution
  • methylene blue solution alkaline according to lǒffler
  • METHYLENEBLUE,ANHYDROUS
  • 3,7-BIS(DIMETHYLAMINO)PHENAZATHIONIUMHCL
  • VISIBLELIGHT-EXCITEDMETHYLENEBLUE
  • D&CBLUENO.1
  • METHYLENE BLUE: 98.5%
  • METHYLTHIONINIUM CHLORIDE(METHYLENE BLUE)
  • METHYLENE BLUE SOLUTION 0.05% SOLUTION
  • Methylene Blue [Ion association reagent for spectrophotometric analysis]
  • [Ion association reagent for spectrophotoMetric analysis]
  • Methylene Blue 
  • METHYLENE BLUE (C.I. 52015) FOR MICROSCO
  • METHYLENE BLUE (C.I. 52015) REAG. PH EUR
  • Methylene Blue, for biological staining
  • Phenothiazin-5-iuM,3,7-bis(diMethylaMino)-, chloride (1:1)
  • Loeffler’s alkaline methylene blue stain solution
  • Methylene Blue – potassium hydroxide solution
  • BORON 1,000PPM FOR ICP
  • FUCHSIN BASIC MICROSCOPY
  • LISTERIA ENRICHMENT SUPLEM. 24ML
  • Methylene Blue Solution (Methanol Solution)[for Cell Staining]
  • Methylene Blue solution, 1% w/v in water
  • Methylene Blue, HARLECO?
  • Methylene Blue, An ethidium bromide alternative for the visualization of nucleic acids in gels
  • SANDOCRYL BLUE B-RL
  • TETRAMETHYLTHIONINE CHLORIDE
  • S NO 1038
  • SWISS BLUE
  • NEISSER'S METHYLENE BLUE
  • NEISSER'S SOLUTION IA
  • Methylene Blue - CAS 61-73-4 - Calbiochem
  • Methylthioninium for system suitability
  • Methylene Blue (C.I. 52015) BioChemica
  • abcolmethyleneblue2b
  • abcolmethyleneblue2bznfree
  • METHYLENE BLUE CONCENTRATE ACC. TO EHR-L ICH, F. MICROSCOPY
  • METHYLENE BLUE, 0.05 WT. % SOLUTION IN W ATER
  • METHYLENE BLUE CONCENTRATED, WATERY,ACCO RDING, TO EHRLICH FOR MICROSCOPY
  • METHYLENE BLUE 0.05 WT. % SOLUTION &
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