2,3,6a alpha, 8,9,9a alpha-Hexahydro-4-methoxy-cyclopenta-(c)furo(2',3',:4,5)furo(2,3-h)chromen-1,11-dion

AFLATOXIN B2 Struktur
7220-81-7
CAS-Nr.
7220-81-7
Bezeichnung:
2,3,6a alpha, 8,9,9a alpha-Hexahydro-4-methoxy-cyclopenta-(c)furo(2',3',:4,5)furo(2,3-h)chromen-1,11-dion
Englisch Name:
AFLATOXIN B2
Synonyma:
AF B2;2,3,6aB1;8,9,9aB1;AFLATOXIN B2;Aflatoxine B2;AFLATOXIN B2(RG);Aflatoxin B2;AF B2;dihydroaflatoxinb1;Dihydroaflatoxin B1;Dihydroafflatoxin B1
CBNumber:
CB0236746
Summenformel:
C17H14O6
Molgewicht:
314.29
MOL-Datei:
7220-81-7.mol

2,3,6a alpha, 8,9,9a alpha-Hexahydro-4-methoxy-cyclopenta-(c)furo(2',3',:4,5)furo(2,3-h)chromen-1,11-dion Eigenschaften

Schmelzpunkt:
286-289 °C
alpha 
D -492° (c = 0.1 in CHCl3)
Siedepunkt:
373.98°C (rough estimate)
Dichte
1.2564 (rough estimate)
Brechungsindex
1.4800 (estimate)
Flammpunkt:
11 °C
storage temp. 
2-8°C
Löslichkeit
DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 12 mg/ml
Wasserlöslichkeit
15mg/L(temperature not stated)
Merck 
13,180
BRN 
1355115
LogP
1.802 (est)
CAS Datenbank
7220-81-7
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher T+,T,F,Xn
R-Sätze: 45-26/27/28-39/23/24/25-23/24/25-11-65-48/23/24/25-36/38-46-36-20/21/22
S-Sätze: 53-36-45-36/37-26-62-28-16
RIDADR  UN 3462 6.1/PG 1
WGK Germany  3
RTECS-Nr. GY1722000
10
HazardClass  6.1(a)
PackingGroup  I
HS Code  29322090
Giftige Stoffe Daten 7220-81-7(Hazardous Substances Data)
Toxizität LD50 orally in day old duckling: 84.8 mg/50 gm body wt (Carnaghan)
Bildanzeige (GHS) GHS hazard pictogramsGHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H340 Kann genetische Defekte verursachen. Keimzellmutagenität Kategorie 1B Achtung GHS hazard pictogramssrc="/GHS08.jpg" width="20" height="20" />
H350 Kann Krebs verursachen. Karzinogenität Kategorie 1A Achtung GHS hazard pictogramssrc="/GHS08.jpg" width="20" height="20" />
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P262 Nicht in die Augen, auf die Haut oder auf die Kleidung gelangen lassen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

2,3,6a alpha, 8,9,9a alpha-Hexahydro-4-methoxy-cyclopenta-(c)furo(2',3',:4,5)furo(2,3-h)chromen-1,11-dion Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R45:Kann Krebs erzeugen.
R26/27/28:Sehr giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
R39/23/24/25:Giftig: ernste Gefahr irreversiblen Schadens durch Einatmen, Berührung mit der Haut und durch Verschlucken.
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
R11:Leichtentzündlich.
R65:Gesundheitsschädlich: kann beim Verschlucken Lungenschäden verursachen.
R48/23/24/25:Giftig: Gefahr ernster Gesundheitsschäden bei längerer Exposition durch Einatmen, Berührung mit der Haut und durch Verschlucken.
R36/38:Reizt die Augen und die Haut.
R46:Kann vererbbare Schäden verursachen.
R36:Reizt die Augen.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-Sätze Betriebsanweisung:

S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S62:Bei Verschlucken kein Erbrechen herbeiführen. Sofort ärztlichen Rat einholen und Verpackung oder dieses Etikett vorzeigen.

Chemische Eigenschaften

off-white powder

Verwenden

Aflatoxin B2 is the minor analogue of the blue fluorescent family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Alfatoxins are one of the most potent mycotoxins known but are in fact "pre-toxins", requiring metabolic activation to the toxic principle. Aflatoxins are found widely in nature in trace amounts, particularly in grains and nuts. The toxicity of these metabolites was first recognised in the 1950s and their structures elucidated in 1963. Aflatoxins have been extensively reviewed.

Definition

ChEBI: An aflatoxin having a hexahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.

Allgemeine Beschreibung

Aflatoxin B2 is one of the fungal metabolic products produced in food and feed, contaminated by?Aspergillus?species.

Sicherheitsprofil

Confirmed human carcinogen with experimental tumorigenic data. Poison by ingestion. Mutation data reported. When heated to decomposition it emits acrid smoke and fumes. See also various aflatoxins.

mögliche Exposition

Aflatoxins are a group of toxic metabolites produced by certain types of fungi. Aflatoxins are not commercially manufactured; they are naturally occurring contaminants that are formed by fungi on food during conditions of high temperatures and high humidity. Most human exposure to aflatoxins occurs through ingestion of contaminated food. The estimated amount of aflatoxins that Americans consume daily is estimated to be 0.15 0.50 μg. Grains, peanuts, tree nuts, and cottonseed meal are among the more common foods on which these fungi grow. Meat, eggs, milk, and other edible products from animals that consume aflatoxincontaminated feed may also contain aflatoxins. Aflatoxins can also be breathed in

Versand/Shipping

UN3172 Toxins, extracted from living sources, solid or liquid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Inkompatibilitäten

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

Waste disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Use of oxidizing agents, such as hydrogen peroxide or 5% sodium hypochlorite bleach. Acids and bases may also be used.

2,3,6a alpha, 8,9,9a alpha-Hexahydro-4-methoxy-cyclopenta-(c)furo(2',3',:4,5)furo(2,3-h)chromen-1,11-dion Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2,3,6a alpha, 8,9,9a alpha-Hexahydro-4-methoxy-cyclopenta-(c)furo(2',3',:4,5)furo(2,3-h)chromen-1,11-dion Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 126)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Mojin Biotechnology Co., Ltd
+8613288715578
sales@hbmojin.com China 12456 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32480 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3620 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083
scglp@glp-china.com CHINA 1824 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282
alice@crovellbio.com China 8823 58
Hubei Ipure Biology Co., Ltd
+8613367258412
ada@ipurechemical.com China 10326 58
HONG KONG IPURE BIOLOGY CO.,LIMITED
86 18062405514 18062405514
ada@ipurechemical.com CHINA 3465 58
Finetech Industry Limited
+86-27-87465837 +8618971612321
info@finetechnology-ind.com China 9702 58
Shijiazhuang Tongyang Import and Export Co., LTD
18031361688;
admin@sjztongyang.com China 987 58
Guangzhou TongYi biochemistry technology Co.,LTD
+8613073028829
mack@tongyon.com China 2996 58

7220-81-7(2,3,6a alpha, 8,9,9a alpha-Hexahydro-4-methoxy-cyclopenta-(c)furo(2',3',:4,5)furo(2,3-h)chromen-1,11-dion)Verwandte Suche:


  • AFLATOXIN B2
  • (6ar-cis)-hexahydro-4-methoxy
  • ,9,9a-alpha-hexahydro-4-methoxy-
  • 2,3,6aalpha,8,9,9aalpha-hexahydro-4-methoxycyclopenta(c)furo(3’,2’:4,5)furo(2,
  • Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6aalpha,8,9,9aalpha-hexahydro-4-methoxy-
  • Dihydroafflatoxin B1
  • Dihydroaflatoxin B1
  • dihydroaflatoxinb1
  • 2,3,6aalpha,8,9,9aalpha-hexahydro-4-methoxycyclopenta[c]furo[2',3':4,5]furo[2,3-h]chromene-1,11-dione
  • AF B2
  • Aflatoxin B2;AF B2
  • aflatoxin b2 solution
  • aflatoxin b2solution
  • AFLATOXIN B2(RG)
  • dihydroaflatoxine b1
  • AFLATOXIN B2 FROM ASPERGILLUS FLAVUS
  • AFLATOXIN B2-LOESUNG 5 NG/MYL IN METHANO
  • AFLATOXIN B(2) FROM ASPERGILLUS FLAVUS, VIAL WITH 10 MG
  • AflatoxinB2,crystalline
  • 3-h)(1)benzopyran-1,11-dione
  • 4-Methoxy-2,3,6a,8,9,9a-hexahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-H]chromene-1,11-dione
  • 9aalpha-hexahydro-4-methoxy-
  • cyclopenta(c)furo(3’,2’:4,5)furo(2,3-h)(1)benzopyran-1,11-dione,2,3,6a-alpha,8
  • cyclopenta(c)furo(3’,2’:4,5)furo(2,3-h)(1)benzopyran-1,11-dione,2,3,6aalpha,8,
  • Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,8,9,9a-hexahydro-4-methoxy-, (6aR-cis)-
  • (6aR)-2,3,6aα,8,9,9aα-Hexahydro-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione
  • (6aR,9aS)-2,3,6a,8,9,9a-Hexahydro-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione
  • Aflatoxine B2
  • Aflatoxin B2 Dihydroaflatoxine B1
  • Aflatoxin B2 Solution in Acetonitrile, 100μg/mL
  • Aflatoxin B2 0.5ug/ml in ACN
  • Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione,2,3,6a,8,9,9a-hexahydro-4-methoxy-, (6aR,9aS)-
  • AflatoxinB2Solution,3mg/L
  • Aflatoxin B2, 98%, from Aspergillus flavus
  • (6aR,9aS)-4-methoxy-2,3,9,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11(6aH,8H)-dione
  • 2,3,6aB1
  • 8,9,9aB1
  • -hexahydro-4-methoxycyclopenta[c]furo[2',3':4,5]furo[2,3-h]chromene-1,11-dione
  • 7220-81-7
  • C17H14O6
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