Naratriptan

Naratriptan Struktur
121679-13-8
CAS-Nr.
121679-13-8
Englisch Name:
Naratriptan
Synonyma:
Naratriptan;Naratriptan1;Naratriptane;Naratriptan(Amerge);Naratriptan, 10 mM in DMSO;AMERGE; NARAMIG; GR-85548A;N-methyl-3-(1-methyl-4-piperidinyl)-1H-Indole-5-ethanesulfonamide;N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide;N-Methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide;Inhibitor,GR-85548A,5-hydroxytryptamine Receptor,inhibit,Serotonin Receptor,5-HT Receptor,Naratriptan
CBNumber:
CB1874790
Summenformel:
C17H25N3O2S
Molgewicht:
335.46
MOL-Datei:
121679-13-8.mol

Naratriptan Eigenschaften

Schmelzpunkt:
170-171°
Siedepunkt:
541.3±60.0 °C(Predicted)
Dichte
1.227±0.06 g/cm3(Predicted)
pka
11.52±0.40(Predicted)

Sicherheit

Naratriptan Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Naratriptan is a triptan drug that is used for the treatment of migraine headaches.

Allgemeine Beschreibung

Naratriptan, the third triptan approved in 1998, is one of themost lipophilic triptans marketed to date. It has a much improvedbioavailability (63% in men and 74% in women), agreater affinity for 5-HT1B/1D receptors (3–6 times), and alower recurrence rate than sumatriptan because of its muchlonger elimination half-life. Naratritan also has a favorableCNS side effect profile when compared with sumatriptanor zolmitriptan because of its metabolic stability,thereby lacking a N-demethylated active metabolite and asignificant renal excretion ( 70% of naratriptan is excretedunchanged and the rest of the administered dose is degradedvia several CYP isozymes).

Naratriptan Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Naratriptan Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 104)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Xiamen Wonderful Bio Technology Co., Ltd.
+8613043004613
Sara@xmwonderfulbio.com China 283 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718; +8613336195806
sales@capot.com China 29735 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29845 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49975 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32435 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626
eric@witopchemical.com China 23541 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15106 58
Baoji Guokang Healthchem Co., Ltd.
+86-0917-3909592 +86-13892490616
gksales1@gk-bio.com China 9209 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894
shawn@hirisunpharm.com CHINA 9911 58

121679-13-8()Verwandte Suche:


  • Naratriptan
  • Naratriptane
  • N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide
  • Naratriptan(Amerge)
  • N-Methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide
  • Naratriptan1
  • AMERGE; NARAMIG; GR-85548A
  • N-methyl-3-(1-methyl-4-piperidinyl)-1H-Indole-5-ethanesulfonamide
  • NaratriptanQ: What is Naratriptan Q: What is the CAS Number of Naratriptan Q: What is the storage condition of Naratriptan
  • Inhibitor,GR-85548A,5-hydroxytryptamine Receptor,inhibit,Serotonin Receptor,5-HT Receptor,Naratriptan
  • Naratriptan, 10 mM in DMSO
  • 121679-13-8
  • 21679-13-8
  • API
  • Indoline & Oxindole
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