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ChemicalBook > Produktkatalog >Aktive pharmazeutische Wirkstoffe (APIs) >Antipyretische Analgetika >Nicht-steroidale Entzündungshemmer (NSAIDS) >4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidindion

4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidindion Produkt Beschreibung

CAS-Nr.129-20-4
Bezeichnung:4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidindion
Englisch Name:OXYPHENYL BUTAZONE
Synonyma:
bm1;BM 1;Flogal;Frabel;g27202;Iridil;Mysite;Neofen;Oxalid;Reumox
CBNumber:CB2133346
Summenformel:C19H20N2O3
Molgewicht:324.37
MOL-Datei:129-20-4.mol
4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidindion physikalisch-chemischer Eigenschaften
Schmelzpunkt:: 109-111°C
Siedepunkt:: 462.71°C (rough estimate)
Dichte: 1.2118 (rough estimate)
Brechungsindex: 1.6140 (estimate)
storage temp. : Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Löslichkeit: DMSO: soluble10mg/mL, clear
pka: pKa 4.7/10.0±0.2(H2O,t =25,Iundefined) (Uncertain)
Aggregatzustand: powder
Farbe: white to brown
CAS Datenbank: 129-20-4(CAS DataBase Reference)
Sicherheit
Kennzeichnung gefährlicher: Xn,N
R-Sätze:: 22-50
S-Sätze:: 61
RIDADR : UN 3077 9 / PGIII
WGK Germany : 3

4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidindion Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften
Light Beige Solid
Verwenden
Anti-inflammatory;Cyclooxygenase inhibito
Definition
ChEBI: A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following asso iation with blood dyscrasis and Stevens-Johnson syndrome.
Trademarks
Tandearil (Novartis);Algi-tandril;Anarreumol-b;Artzone;Buteril;Campozim;Defolgin;Difmedol;Dolo-phlogase;Dolo-tandril;Fibutrox;Gp 40705;Iltazon;Iltoxon;Inflamil;Mindaril;Miyadril;Oflamin;Otone;Oxybutazone;Oxybutol;Oxyperol;Oxyphenbutone;Phlogistol;Phlogont;Phloguran;Pilabutina;Realin;Rheumapax;Segudol;Suganril;Tanal;Tandacot;Teneral;Vefren.
Weltgesundheitsorganisation (WHO)
Oxyphenbutazone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1955 for the treatment of rheumatic disorders. It is one of the active metabolites of phenylbutazone and has a similar spectrum of activity including an association with serious and sometimes fatal adverse reactions, notably cases of aplastic anaemia and agranulocytosis. Many national drug regulatory authorities consider that more recently introduced drugs offer a safer alternative for most, if not all, patients requiring antiinflammatory agents. Although oxyphenbutazone has been widely withdrawn it remains available in some countries.
4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidindion Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidindion Anbieter Lieferant Produzent Hersteller Vertrieb Händler.      Global( 32)Lieferanten     
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Mainchem Co., Ltd.
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129-20-4(4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidindion)Verwandte Suche:
4'-Hydroxybutyranilid Hydrazobenzol 4-Butyl-2-phenyl-1-[4-(phenylmethoxy)phenyl]pyrazolidin-3,5-dion N,N'-Diphenylmalonamid 4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidindion 2'-Phenylacetohydrazid Hydrazodicarbaldehyd 4-Methyl-1-phenyl-3-pyrazolidon 1-Phenyl-3-pyrazolidon Mofebutazon 4-Butyl-1,2-diphenyl-3,5-pyrazoli-dindion
Hydroxy phenylbutazone Grovaril 4-butyl-1-(4-hydroxyphenyl)-2-phenyl-pyrazolidine-3,5-dione 4-butyl-1-(4-hydroxyphenyl)-2-phenylpyrazolidine-3,5-dione 4-butyl-1-(4-hydroxyphenyl)-2-phenyl-pyrazolidine-3,5-quinone 4-Butyl-1-(4-hydroxyphenyl)-2-phenyl- NSC 526053 Ro 04-4410 Oxyphenbutazone Solution, 100ppm LABOTEST-BB LT00134684 OXYPHENYL BUTAZONE 1-(p-Hydroxyphenyl)-2-phenyl-3,5-dioxo-4-N-butylpyrazolidine 1-(p-Hydroxyphenyl)-2-phenyl-4-butyl-3,5-pyrazolidinedione 1-(p-hydroxyphenyl)-2-phenyl-4-butylpyrazolidine-3,5-dione 1-Phenyl-2-(p-hydroxyphenyl)-3,5-dioxo-4-butylpyrazolidine 1-phenyl-2-(p-hydroxyphenyl)-3,5-dioxo-4-n-butylpyrazolidine 1-p-hydroxyphenyl-2-phenyl-3,5-dioxo-4-n-butylpyrazolidine 3,5-Dioxo-1-phenyl-2-(p-hydroxyphenyl)-4-N-butylpyrazolidene 3,5-Pyrazolidinedione, 4-butyl-1-(4-hydroxyphenyl)-2-phenyl- 3,5-Pyrazolidinedione, 4-butyl-1-(p-hydroxyphenyl)-2-phenyl- 3,5-pyrazolidinedione,4-butyl-1-(4-hydroxyphenyl)-2-phenyl 4-Butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidinedione 4-Butyl-1-(p-hydroxyphenyl)-2-phenyl-3,5-pyrazolidinedione 4-butyl-1-(p-hydroxyphenyl)-2-phenyl-5-pyrazolidinedione 4-Butyl-2-(4-hydroxyphenyl)-1-phenyl-3,5-dioxopyrazolidine 4-Butyl-2-(p-hydroxyphenyl)-1-phenyl-3,5-pyrazolidinedione Artroflog BM 1 bm1 Butaflogin butanora Butanova Butapirone Butazonic Californit Crovaril Deflogin Etrozolidina Flamaril Flanaril Flogal Floghene Flogistin Flogitolo Flogodin Flogoril Flogostop Flopirina Frabel G 27202 g27202 Idrobutazina Infamil Infammil Ipabutona Iridil Isobutazina Isobutil
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