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OXYPHENYL BUTAZONE

OXYPHENYL BUTAZONE
OXYPHENYL BUTAZONE structure
CAS No.
129-20-4
Chemical Name:
OXYPHENYL BUTAZONE
Synonyms
bm1;BM 1;Flogal;Frabel;g27202;Iridil;Mysite;Neofen;Oxalid;Reumox
CBNumber:
CB2133346
Molecular Formula:
C19H20N2O3
Formula Weight:
324.37
MOL File:
129-20-4.mol

OXYPHENYL BUTAZONE Properties

Melting point:
109-111°C
Boiling point:
462.71°C (rough estimate)
Density 
1.2118 (rough estimate)
refractive index 
1.6140 (estimate)
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
DMSO: soluble10mg/mL, clear
pka
pKa 4.7/10.0±0.2(H2O,t =25,Iundefined) (Uncertain)
form 
powder
color 
white to brown
CAS DataBase Reference
129-20-4(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn,N
Risk Statements  22-50
Safety Statements  61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.

OXYPHENYL BUTAZONE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0540 Oxyphenbutazone ≥98% (HPLC) 129-20-4 10mg $109 2018-11-13 Buy
Sigma-Aldrich SML0540 Oxyphenbutazone ≥98% (HPLC) 129-20-4 50mg $420 2018-11-13 Buy
Cayman Chemical 18723 Oxyphenbutazone ≥98% 129-20-4 1mg $25 2018-11-13 Buy
Cayman Chemical 18723 Oxyphenbutazone ≥98% 129-20-4 5mg $56 2018-11-13 Buy
Cayman Chemical 18723 Oxyphenbutazone ≥98% 129-20-4 10mg $88 2018-11-13 Buy

OXYPHENYL BUTAZONE Chemical Properties,Uses,Production

Chemical Properties

Light Beige Solid

Uses

Anti-inflammatory;Cyclooxygenase inhibito

Definition

ChEBI: A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following asso iation with blood dyscrasis and Stevens-Johnson syndrome.

brand name

Tandearil (Novartis);Algi-tandril;Anarreumol-b;Artzone;Buteril;Campozim;Defolgin;Difmedol;Dolo-phlogase;Dolo-tandril;Fibutrox;Gp 40705;Iltazon;Iltoxon;Inflamil;Mindaril;Miyadril;Oflamin;Otone;Oxybutazone;Oxybutol;Oxyperol;Oxyphenbutone;Phlogistol;Phlogont;Phloguran;Pilabutina;Realin;Rheumapax;Segudol;Suganril;Tanal;Tandacot;Teneral;Vefren.

World Health Organization (WHO)

Oxyphenbutazone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1955 for the treatment of rheumatic disorders. It is one of the active metabolites of phenylbutazone and has a similar spectrum of activity including an association with serious and sometimes fatal adverse reactions, notably cases of aplastic anaemia and agranulocytosis. Many national drug regulatory authorities consider that more recently introduced drugs offer a safer alternative for most, if not all, patients requiring antiinflammatory agents. Although oxyphenbutazone has been widely withdrawn it remains available in some countries.

OXYPHENYL BUTAZONE Preparation Products And Raw materials

Raw materials

Preparation Products


OXYPHENYL BUTAZONE Suppliers

Global( 32)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32607 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
LGM Pharma 1-(800)-881-8210
615-250-9817 inquiries@lgmpharma.com United States 1950 70
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32469 50
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979
021-34692979 info@tsbiochem.com China 8103 58
Sigma-Aldrich 021-61415566 800-819-3336(Tel) 400-620-3333(Mobile)
021-61415567 orderCN@sial.com China 28795 80
Alta Scientific Co., Ltd. (0086) 22-6537-8550; 185-2256-9193; 185-2256-9194
(0086) 22-2532-9655 contact@altascientific.com China 8332 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885
021-65675885 info@efebio.com China 9976 58
ShangHai Biochempartner Co.,Ltd 13720134139
candy@biochempartner.com China 4979 62
Shenzhen Xinyaoxiong Industrial Co. Ltd. 0755-33204565 Sales QQ:2280077800(WeChat)
Advantage suppliers add cooperation QQ:577116998 szxys126@126.com China 54593 58

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