DGAT-3

701232-20-4

CAS-Nr.: 701232-20-4

Englisch Name:: DGAT-3

Synonyma:: DGAT-3;CS-120;T-863;T 863;trans-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexaneacetic acid;trans-Cyclohexaneacetic-acid,-4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl];trans-2-(4-(4-(4-aMino-7,7-diMethyl-7H-pyriMido[4,5-b][1,4]oxazin-6-yl)phenyl)cyclohexyl)acetic acid;Mino-7,7-diMethyl-2-((1r,4r)-4-(4-(4-a7H-pyriMido[4,5-b][1,4]oxazin-6-yl)phenyl)cyclohexyl)acetic acid;Cyclohexaneacetic acid, 4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]-, trans-;2-((1,4-trans)-4-(4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)- phenyl)cyclohexyl)acetic acid;Diglyceride acyltransferase,inhibit,acyl-CoA:cholesterol acyltransferase,T 863,T-863,T863,Inhibitor,Acyltransferase,mono- acylglycerol acyltransferase,Diacylglycerol acyltransferase

CBNumber:: CB31872285

Summenformel:: C22H26N4O3

Molgewicht:: 394.47

MOL-Datei:: 701232-20-4.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 54

DGAT-3 Eigenschaften

Siedepunkt:: 616.6±55.0 °C(Predicted)

Dichte: 1.36±0.1 g/cm3(Predicted)

storage temp.: 2-8°C

Löslichkeit: DMSO: soluble15mg/mL (clear solution)

pka: 4.72±0.10(Predicted)

Aggregatzustand: powder

Farbe: white to beige

Sicherheit

WGK Germany	3

DGAT-3 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

T863 has been used as a diglyceride acyltransferase (DGAT1) inhibitor:

to provide the opportunity to precisely control the DGAT inhibition
to treat mouse embryonic fibroblasts (MEFs) to analyse lipid droplet biogenesis
to specifically block neutral?lipid synthesis?and lipid droplet formation in HT-1080 cells
to block lipid droplet (LD) formation

Biochem/physiol Actions

T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. T863 causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice.

DGAT-3 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

DGAT-3 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 54)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2923	55

701232-20-4()Verwandte Suche:

N,N-Dimethyl-anilin trans-4-Aminocyclohexan-1-ol

DGAT-3
Cyclohexaneacetic acid, 4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]-, trans-
trans-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexaneacetic acid
Mino-7,7-diMethyl-2-((1r,4r)-4-(4-(4-a7H-pyriMido[4,5-b][1,4]oxazin-6-yl)phenyl)cyclohexyl)acetic acid
trans-2-(4-(4-(4-aMino-7,7-diMethyl-7H-pyriMido[4,5-b][1,4]oxazin-6-yl)phenyl)cyclohexyl)acetic acid
2-((1,4-trans)-4-(4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)- phenyl)cyclohexyl)acetic acid
T-863;T 863
CS-120
trans-Cyclohexaneacetic-acid,-4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]
Diglyceride acyltransferase,inhibit,acyl-CoA:cholesterol acyltransferase,T 863,T-863,T863,Inhibitor,Acyltransferase,mono- acylglycerol acyltransferase,Diacylglycerol acyltransferase
701232-20-4