Isoxazol

Isoxazole Struktur
288-14-2
CAS-Nr.
288-14-2
Bezeichnung:
Isoxazol
Englisch Name:
Isoxazole
Synonyma:
ISOXAZOLE;Isooxazole;Isoxazolec;1,2-Oxazole;Isoxazole>Isoxazole,99%;Isoxazole 99%;ISOXAZOLE 98+%;Isoxazole, 98.5%;Different oxazole
CBNumber:
CB3485864
Summenformel:
C3H3NO
Molgewicht:
69.06
MOL-Datei:
288-14-2.mol

Isoxazol Eigenschaften

Schmelzpunkt:
-67.1°C
Siedepunkt:
93-95 °C(lit.)
Dichte
1.078 g/mL at 25 °C(lit.)
Dampfdichte
2.4 (vs air)
Brechungsindex
n20/D 1.427(lit.)
Flammpunkt:
48 °F
storage temp. 
2-8°C
Löslichkeit
167g/l
pka
-2.0(at 25℃)
Aggregatzustand
clear liquid
Farbe
Colorless to Light yellow
BRN 
103773
InChIKey
CTAPFRYPJLPFDF-UHFFFAOYSA-N
CAS Datenbank
288-14-2(CAS DataBase Reference)
NIST chemische Informationen
Isoxazole(288-14-2)
EPA chemische Informationen
Isoxazole (288-14-2)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher F,Xi
R-Sätze: 11
S-Sätze: 16-23/33-33-29-7/9
RIDADR  UN 1993 3/PG 2
WGK Germany  3
10
Hazard Note  Highly Flammable
TSCA  Yes
HazardClass  3
PackingGroup  II
HS Code  29349990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H225 Flüssigkeit und Dampf leicht entzündbar. Entzündbare Flüssigkeiten Kategorie 2 Achtung GHS hazard pictogramssrc="/GHS02.jpg" width="20" height="20" /> P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
Sicherheit
P210 Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.

Isoxazol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R11:Leichtentzündlich.

S-Sätze Betriebsanweisung:

S16:Von Zündquellen fernhalten - Nicht rauchen.
S33:Maßnahmen gegen elektrostatische Aufladungen treffen.
S29:Nicht in die Kanalisation gelangen lassen.
S7/9:Behälter dicht geschlossen an einem gut gelüfteten Ort aufbewahren.

Beschreibung

Isoxazole, an important class of heterocycles, is a five membered heterocyclic compound that exhibits various pharmacological actions. It is present in some natural products such as ibotenic acid and is also used as a foundation for several drugs such as the COX-2 inhibitor valdecoxib and anti-inflammatory drugs. Isoxazoles are largely applied in the area of pharmaceuticals and therapeutics, including insecticidal, antibacterial, antibiotic, antitumour, antifungal, antituberculosis, anticancer and ulcerogenic. Besides, it has a great effect on reducing blood glucose, eliminating pain, resisting inflammation, killing harmful bacteria, controlling and reducing the risk of HIV.

Chemische Eigenschaften

A colorless liquid resembling pyridine. It is soluble in water at room temperature up to six times its volume.

Verwenden

Natural insecticide.

Definition

ChEBI: Isoxazole is a monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles. It is a mancude organic heteromonocyclic parent, a monocyclic heteroarene and a member of isoxazoles.

synthetische

Isoxazoles can be synthesized by various methods, such as the 1,3-dipolar cycloaddition reaction of nitrile oxides with alkynes, the reaction of hydroxylamine with 1,3-diketones or propiolic acid derivatives, etc.
www.organic-chemistry.org

Allgemeine Beschreibung

Isoxazole(288-14-2) are described as inhibitors of acetylcholinesterase (AChE). Isoxazole ligands bind to and inhibit the Sxc- antiporter.

Hazard

Narcotic and psychomimetic effects.

Einzelnachweise

https://en.wikipedia.org/wiki/Isoxazole
https://pubchem.ncbi.nlm.nih.gov/compound/9254

Isoxazol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Isoxazol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 250)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806
sales@capotchem.com China 29797 60
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29914 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873
sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 47465 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051
joe@yuhengpharm.com CHINA 21149 58
Hubei Ipure Biology Co., Ltd
+8613367258412
ada@ipurechemical.com China 10326 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
sales@tnjchem.com China 34572 58
HONG KONG IPURE BIOLOGY CO.,LIMITED
86 18062405514 18062405514
ada@ipurechemical.com CHINA 3465 58
WinWin Chemical CO., Limited
+86-0086-577-64498589 +86-15355981851
sales@win-winchemical.com China 13854 58

288-14-2(Isoxazol)Verwandte Suche:


  • ISOXAZOLE 98+%
  • 1,2-Oxazole
  • Isoxazole,99%
  • Different oxazole
  • Isoxazole 99%
  • ISOXAZOLE
  • 1-Oxa-2-azacyclopentadiene
  • Isooxazole
  • Isoxazole, 98.5%
  • Isoxazole>
  • Isoxazolec
  • Isoxazole (6CI, 7CI, 8CI, 9CI, ACI)
  • Entacapone Impurity 31
  • 288-14-2
  • Isoxazoles
  • Heterocyclic Building Blocks
  • Building Blocks
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Heterocyclic Building Blocks
  • Isoxazoles
  • Building Blocks
  • Isoxazoles, Oxadiazoles, Oxazoles
  • pharmacetical
  • Boronic ester
  • Isoxazole
  • Organoborons
  • Thiophens
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