4-Hydroxy-3-(3-(4'-brom-4-biphenylyl)-1,2,3,4-tetrahydro-1-naphthyl)cumarin

4-Hydroxy-3-(3-(4'-brom-4-biphenylyl)-1,2,3,4-tetrahydro-1-naphthyl)cumarin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R27/28:Sehr giftig bei Berührung mit der Haut und beim Verschlucken.
R48/24/25:Giftig: Gefahr ernster Gesundheitsschäden bei längerer Exposition durch Berührung mit der Haut und durch Verschlucken.
R50/53:Sehr giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.

S-Sätze Betriebsanweisung:

S1/2:Unter Verschluss und für Kinder unzugänglich aufbewahren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S60:Dieses Produkt und sein Behälter sind als gefährlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.

Beschreibung

Brodifacoum is a 4-hydroxycoumarin anticoagulant that acts as a vitamin K antagonist. It was registered as a pesticide in 1979 in the United States although in 2008 it was made a restricted use pesticide by the Environmental Protection Agency. This means it can only be used by certified pesticide applicators; however, the makers of D-Con which contains 0.005% brodifacoum by weight have challenged this and brodifacoum is currently available in D-Con and in various other pesticide products for the eradication of mice and rats although it is also used on larger mammals such as possums. Brodifacoum currently remains available to the general public.

Chemische Eigenschaften

White Solid

Verwenden

Brodifacoum is a highly lethal vitamin K antagonist anticoagulant poison. In recent years, Broadifacoum, has become one of the world's most widely used pesticides.

Hazard

Poison, anticoagulant.

Environmental Fate

Brodifacoum, like other hydroxycoumarins, interferes with the production of vitamin K–dependent coagulation factors. Vitamin K is a cofactor for the carboxylation of specific glutamic acid groups in coagulation factors II (prothrombin), VII, IX, and X. During this step, vitamin K is oxidized to vitamin K 2,3-epoxide. The regeneration of vitamin K by vitamin K 2,3-epoxide reductase is prevented by brodifacoum. As a result, dysfunctional decarboxy-coagulation factors are produced and coagulation is impaired. Brodifacoum is over 100 times more potent than warfarin on a molar basis in rats.

Stoffwechselwegen

The fate of brodifacoum in soils and plants has not been studied in detail because the compound is usually applied as a pelleted bait or in a wax block. This limits its dissipation in the environment. Studies in animals have been conducted as part of the assessment of safety and to investigate mode of action.

4-Hydroxy-3-(3-(4'-brom-4-biphenylyl)-1,2,3,4-tetrahydro-1-naphthyl)cumarin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

56073-10-0(4-Hydroxy-3-(3-(4'-brom-4-biphenylyl)-1,2,3,4-tetrahydro-1-naphthyl)cumarin)Verwandte Suche:

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• KLERAT
• KLERAT(R)
• FORWARAT
• HAVOC
• BROBAIT
• BRODIFACOUM
• 3-(3-(4'-bromo-(1,1'-biphenyl)-4-yl)-1,2,3,4-tetrahydro-1-naphthyl)-4-hydroxy-2h-1-benzopyran-2-one
• 3-(3-(4'-Bromo-(1,1'-biphenyl)-4-yl)-1,2,3,4-tetrahydro-1-napthalenyl)-4-hydroxycoumarin
• SOREX BRODIFACOUM RAT
• TALON(R)
• NOFAR(R)
• MOUSE BAIT
• WEATHERBLOK(R)
• 2h-1-benzopyran-2-one,3-(3-(4’-bromo(1,1’-biphenyl)-4-yl)-1,2,3,4-tetrahydro-1
• 3-(3-(4’-bromo-1,1’-biphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthyl)-4-hydroxyc
• 3-(3-(4’-bromobiphenyl-4-yl)-1,2,3,4-tetrahydronaphth-1-yl)-4-hydroxycoumari
• 3-[3-(4’-bromo[1,1’-biphenyl]4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl]-4-hydrox
• 3-[3-[4’-Bromo[1,1’-biphenyl]-4-yl]-1,2,3,4-tetrahydro-1-naphthalenyl]-4-hydroxy-2H-benzopyran-2-one
• 4-hydroxy-3-(3-(4’-bromo-4-biphenylyl)-1,2,3,4-tetrahydro-1-naphthyl)coumarin
• brodifakum
• bromfenacoum
• coumarin,3-(3-(4’-bromo-1,1’-biphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthyl)-4-h
• -naphthalenyl)-4-hydroxy-
• pp581
• BRODIFACOUM, 50MG, NEAT
• BRODIFACOUM PESTANAL 100 MG
• 3-[3-(4'-Bromo[1,1'-biphenyl]-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl]-4-hydroxy-2H-1-benzopyran-2-one
• Brodifacoun
• 2H-1-Benzopyran-2-one, 3-3-(4-bromo1,1-biphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl-4-hydroxy-
• brodifacoum (bsi,iso)
• 4-hydroxy-3-(3-(4'-bromo-4-biphenylyl)-1,2,3,4-tetrahydro-1-naphthyl)coumarin brodifacoum
• ICI 581
• Matikus
• 3-[3-（4'-bromobiphen-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl]-4-hydroxycoumarin
• 3-[3-[4-(4-Bromophenyl)phenyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-2-hydroxychromen-4-one
• Brodima
• Brofenacoum
• BrodiMat
• BrodiMax Forte Pasta
• Klerat Block
• pp-581
• talonrodenticide
• volid
• wba8119
• y-2h-1-benzopyran-2-one
• ydroxy-
• 3-[3-(4-Bromo biphenyl-4)-1,2,3,4-tetrahydrogen naphthyl-1-yl]-4-hydroxy coumarin
• BRODIFACOUM (TALON RODENTICIDE)
• Ratak Plus
• Talon Rat Bait
• 3-[3-[4-(4-bromophenyl)phenyl]-1,2,3,4-tetrahydronaphthalen-1-yl]-4-hydroxychromen-2-one
• Broadifacoum
• (66052-95-7) brodifacoum
• Brodifacoum (Mixture of Diastereomers)
• Effectively kill rats / mouse Rodenticide Pellets Brodifacoum 0.005% CAS 56073-10-0
• Rat Poison Rodenticide 98%TC
• Brodifacoum-d4 (Mixture of Diastereomers)
• Rat Poison Rodenticide