PURVALANOL A
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- CAS-Nr.
- 212844-53-6
- Englisch Name:
- PURVALANOL A
- Synonyma:
- NG-60;PurvaL;CH61386;CS-1631;PURVALANOL A;CDKinhibitor;(R)-Purvalanol A;NG 60;NG60;NG-60;PURVALANOLA, >98%;PurvalanolA/CH61386
- CBNumber:
- CB5283664
- Summenformel:
- C19H25ClN6O
- Molgewicht:
- 388.89
- MOL-Datei:
- 212844-53-6.mol
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PURVALANOL A Eigenschaften
- Siedepunkt:
- 590.5±60.0 °C(Predicted)
- Dichte
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- Löslichkeit
- methylene chloride: 50 mg/mL, clear, colorless
- Aggregatzustand
- powder
- pka
- 14.51±0.10(Predicted)
- Farbe
- off-white
- Stabilität:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
PURVALANOL A Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Purvalanol A acts as a potent, cell-permeable CDK inhibitor used in the treatment of cell proliferative disorders. Anti-cancer.
Biologische Aktivität
Cyclin-dependent kinase inhibitor. IC 50 values are 4, 70, 35, 850 and 75 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. Reversibly arrests synchronised cells in G1 and G2, and inhibits cell proliferation and cell death.
PURVALANOL A Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
PURVALANOL A Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 97)Lieferanten
212844-53-6()Verwandte Suche:
- PURVALANOL A
- NG-60
- 6-(3-CHLOROANILINO)-2(1R)-ISOPROPYL-2-HYDROXYETHYLAMINO-9-ISOPROPYLPURINE
- (2R)-2-[[6-[(3-CHLOROPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL
- 2-(1R-ISOPROPOYL-2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE
- 2-(1R-ISOPROPYL-2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYL-PURINE
- CH61386
- 2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanolCDKinhibitor.
- PurvalanolA,CDKinhibitor
- CDKinhibitor
- PurvalanolA/CH61386
- Purvalanol A(NG 60)
- (R)-Purvalanol A
- (R)-2-(6-(3-chlorophenylamino)-9-isopropyl-9H-purin-2-ylamino)-3-methylbutan-1-ol
- NG-60, 2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine
- Purvalanol A - CAS 212844-53-6 - Calbiochem
- NG 60;NG60;NG-60
- CS-1631
- PURVALANOLA, >98%
- PurvaL
- 1-Butanol, 2-[[6-[(3-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-, (2R)-
- PURVALANOL A USP/EP/BP
- (2R)-2-[[6-(3-chloroanilino)-9-propan-2-ylpurin-2-yl]amino]-3-methylbutan-1-ol
- 212844-53-6
- C19H25ClN6O
- BioChemical
- Cell Biology
- Cell Signaling and Neuroscience
- Cell Cycle Regulators
- Cell Cycle
- Apoptosis and Cell Cycle
- Inhibitors
- Signalling
