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PHALLACIDIN

PHALLACIDIN Struktur
26645-35-2
CAS-Nr.
26645-35-2
Englisch Name:
PHALLACIDIN
Synonyma:
PHALLICIDIN;PHALLACIDIN;Phallacidin DISCONTINUED;CYCLO(ALA-2-MERCAPTO-TRP-4;phallacidin from amanita phalloides;Cyclo(Ala-2-Mercapto-Trp-4;5-DIHYDROXY-LEU-VAL-ERYTHRO-3-HYDROXY-D-ASP-CYS-CIS-4-HYDROXY-PRO);-3-hydroxy-d-alpha-aspartyl-l-cysteinyl-cis-4-hydroxy-l-prolyl)cyclic(2-6)-s;cyclic(l-alanyl-2-mercapto-l-tryptophyl-4,5-dihydroxy-l-leucyl-l-valyl-erythro;Cyclo[L-Ala-L-Trp2(1)-4,5-dihydroxy-L-Leu-L-Val-[(3S)-3-hydroxy-D-Asp-]-L-Cys(1)-L-c4Hyp-]
CBNumber:
CB6136097
Summenformel:
C37H50N8O13S
Molgewicht:
846.9
MOL-Datei:
26645-35-2.mol
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PHALLACIDIN Eigenschaften

Dichte
1.1678 (rough estimate)
Brechungsindex
1.7400 (estimate)
Löslichkeit
DMF: Soluble; DMSO: Soluble; Methanol: Soluble; Water: Soluble
Aggregatzustand
White to off-white powder.

Sicherheit

Kennzeichnung gefährlicher T+
R-Sätze: 26/27/28
S-Sätze: 22-36/37/39-45
RIDADR  1544
WGK Germany  3
RTECS-Nr. GT8943000
HazardClass  6.1(a)
PackingGroup  I
HS Code  2934999090

PHALLACIDIN Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R26/27/28:Sehr giftig beim Einatmen, Verschlucken und Berührung mit der Haut.

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).

Beschreibung

Phallacidin is a natural mycotoxin first isolated from the death cap mushroom, A. phalloides. It binds filamentous actin (F-actin) like phalloidin , but contains a carboxyl group for coupling reactions.

Verwenden

Toxin Phallacidin is a weak fluorescent bicyclic peptide probe in aquous solution, Which is isolated from Amanita phalloides mushroom and could be used for blocking F-actin staining by labeled phallotoxins, which promotes actin polymerization.

Definition

ChEBI: A homodetic bicyclic heptapeptide having a sulfide bridge.

Enzyminhibitor

This cyclic heptapeptide toxin (FWfree-acid = 846.92 g/mol; CAS 26645-35-2) from the poisonous green fungus Amanita phalloides stabilizes actin filaments and inhibits actin filament depolymerization. NBD phallacidin is a high-affinity, filamentous actin probe consisting of rabbit actin that is conjugated by reacting its thiol group with 4-chloro-7- nitrobenzofurazan, a yellow-green fluorescent dye. NBD phallacidin (Excitation at 465 nm; Emission at 536 nm) selectively stains F-actin un a manner that is superior to antibody staining, preferably in fixed and permeabilized samples. See Phalloidin

PHALLACIDIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

PHALLACIDIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 38)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 57511 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 18521735133 18521732826;
 market@aladdin-e.com China 25015 65
Shanghai Tauto Biotech Co., Ltd. 021-51320588
tauto@tautobiotech.com China 3989 66
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51471 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9709 58
Chengdu Dianchun Technology Co., Ltd 400-1166-196 18502815961
 cdhxsj@163.com China 14623 60
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088
 3193328036@qq.com China 29797 68
Shanghai Jizhi Biochemical Technology Co. Ltd. 400-400-400-9004166 18616739031
 3007523370@qq.com China 52712 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11289 58

26645-35-2()Verwandte Suche:

4-(Methylthio)butan-2-on 1-Methylpyrrolidin-3-ol 3,6,9-Triazaundecan-1,11-diamin 1,3-Dibutylharnstoff 3,6,9,12-Tetraazatetradecamethylendiamin 5-Amino-4-oxovaleriansure N-(2-Oxopropyl)acetamid N-(1-Methyl-2-oxopropyl)acetamid
  • 5-Dihydroxy-Leu-Val-erythro-3-Hydroxy-D-Asp-Cys-cis-4-Hydroxy-Pro)
  • Cyclo(Ala-2-Mercapto-Trp-4
  • PHALLACIDIN FROM AMANITA PHALLOIDES;CYCLO(ALA-2-MERCAPTO-TRP-4;5-DIHYDROXY-LEU-VAL-ERYTHRO-3-HYDROXY-D-ASP-CYS-CIS-4-HYDROXY-PRO)
  • PHALLACIDIN
  • PHALLICIDIN
  • CYCLO[ALA-2-MERCAPTO-TRP-4,5-DIHYDROXY-LEU-VAL-ERYTHRO-3-HYDROXY-D-ASP-CYS-CIS-4-HYDROXY-PRO]
  • -3-hydroxy-d-alpha-aspartyl-l-cysteinyl-cis-4-hydroxy-l-prolyl)cyclic(2-6)-s
  • cyclic(l-alanyl-2-mercapto-l-tryptophyl-4,5-dihydroxy-l-leucyl-l-valyl-erythro
  • phallacidin from amanita phalloides
  • Cyclo[L-Ala-L-Trp2(1)-4,5-dihydroxy-L-Leu-L-Val-[(3S)-3-hydroxy-D-Asp-]-L-Cys(1)-L-c4Hyp-]
  • 5-DIHYDROXY-LEU-VAL-ERYTHRO-3-HYDROXY-D-ASP-CYS-CIS-4-HYDROXY-PRO)
  • CYCLO(ALA-2-MERCAPTO-TRP-4
  • PHALLACIDIN FROM AMANITA PHALLOIDES;CYCLO(ALA-2-MERCAPTO-TRP-4;5-DIHYDROXY-LEU-VAL-ERYTHRO-3-HYDROXY-D-ASP-CYS-CIS-4-HYDROXY-PRO)
  • Cyclo[L-alanyl-2-mercapto-L-tryptophyl-4,5-dihydroxy-L-leucyl-L-valyl-(3S)-3-hydroxy-D-α-aspartyl-L-cysteinyl-(4S)-4-hydroxy-L-prolyl], cyclic (2→6)-thioether
  • Phallacidin DISCONTINUED
  • 26645-35-2
  • C37H50N8O13S
  • Biochemicals and Reagents
  • BioChemical
  • Auxiliary Proteins
  • Other
  • Proteins and Derivatives
  • marker
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