Orciprenalinsulfat
|
|
|
- CAS-Nr.
- 5874-97-5
- Bezeichnung:
- Orciprenalinsulfat
- Englisch Name:
- Orciprenaline sulfate
- Synonyma:
- METAPROTERENOL SULFATE;alupent;alotec;th-152;metaprel;Astmopent;novasmasol;ORCIPRENALINE SULFATE;dl-Orciprenaline sulfate;METAPROTERENOLSULFATE,USP
- CBNumber:
- CB7226328
- Summenformel:
- C22H36N2O10S
- Molgewicht:
- 520.59
- MOL-Datei:
- 5874-97-5.mol
|
Orciprenalinsulfat Eigenschaften
- Schmelzpunkt:
- 202-203°
- storage temp.
- 2-8°C
- Löslichkeit
- Freely soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
- Farbe
- White to Off-White
- Stabilität:
- Hygroscopic
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
|
|
| R-Sätze: |
20 |
|
|
| S-Sätze: |
36 |
|
|
| WGK Germany |
2 |
|
|
| RTECS-Nr. |
DO2275000 |
|
|
| HS Code |
2922504500 |
|
|
| Toxizität |
LD50 in rats (mg/kg): 42 orally (Goldenthal) |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H332 |
Gesundheitsschädlich bei Einatmen. |
Akute Toxizität inhalativ |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P271, P304+P340, P312 |
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P271 |
Nur im Freien oder in gut belüfteten Räumen verwenden. |
|
Orciprenalinsulfat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R20:Gesundheitsschädlich beim Einatmen.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
White or almost white, slightly hygroscopic, crystalline powder.
Verwenden
Beta2-adrenoceptor agonist; bronchodilator.
Pharmakokinetik
Metaproterenol is a direct-acting resorcinol analogue of isoproterenol. The N-isopropyl is
β-directing, and the combination with the resorcinol ring system enhances the selectivity for the
β2-receptors. It is the least potent of the β2-selective agonists, however, most likely because of
the poor β2-selectivity of the isopropyl group. It has good oral bioavailability being resistant to
COMT and only slowly metabolized by MAO. When administered orally, it has an onset of
approximately 30 minutes with a 4-hour duration. Inhaled metaproterenol can have an onset as
quick as 5 minutes; however, it can be as long as 30 minutes in susceptible individuals.
Metaproterenol is available in tablet, syrup, and inhalation dosage forms and is recommended for
bronchial asthma attacks and treatment of acute asthmatic attacks in children 6 years of age and
older (5% solution for inhalation only). Metaproterenol has the same adverse effect profile as
other adrenergic agonists, but with a decreased incidence of arrhythmias.
Orciprenalinsulfat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Orciprenalinsulfat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 111)Lieferanten
5874-97-5(Orciprenalinsulfat)Verwandte Suche:
- 1-(3,5-dihydroxyphenyl)-1-hydroxy-2-isopropylaminoethanesulfate
- 1-(3,5-dihydroxyphenyl)-2-(isopropylamino)ethanolsulfate
- 3,5-dihydroxy-alpha-((isopropylamino)methyl)benzylalcoholsulfate
- 3,5-dihydroxy-alpha-((isopropylamino)methyl)-benzylalcohosulfate(2:1)(s
- 3-benzenediol,5-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-sulfate(2:1)
- alotec
- metaprel
- novasmasol
- th-152
- METAPROTERENOL HEMISULFATE
- METAPROTERENOL HEMISULFATE SALT
- METAPROTERENOL SULFATE, USP STANDARD
- 3,5-dihydroxy-alpha-((isopropylamino)methyl)-benzyl alcohol sulfate (2:1)
- ORCIPRENALINE SULFATE
- METAPROTERENOLSULFATE,USP
- 1,3-Benzenediol, 5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, sulfate (2:1) (salt) (9CI)
- 3,5-Dihydroxy-a-[(isopropylamino)methyl]benzyl alcohol sulfate (2:1) (salt)
- Astmopent
- Benzyl alcohol, 3,5-dihydroxy-a-[(isopropylamino)methyl]-, sulfate (2:1) (salt) (8CI)
- dl-Metaproterenol sulfate
- dl-Orciprenaline sulfate
- Metaproterenol sulfate (2:1) (salt)
- ORCIPRENALINE SULPHATE(METAPROTERENOL)
- METAPROTERENOL HEMISULFATE USP28
- Metaproterenol Sulfate (200 mg)
- 3,5-Dihydroxy-α-[(isopropylaMino)Methyl]benzyl Alcohol Sulfate
- 5-[1-Hydroxy-2-[(1-Methylethyl)aMino]ethyl]-1,3-benzenediol Sulfate
- Orciprenaline heMisulfate
- Orciprenaline hemisulfate Solution, 100ppm
- Orciprenaline sulfate CRS
- Orciprenaline for system suitability CRS
- 5-(1-hydroxy-2-(isopropylamino)ethyl)benzene-1,3-diol hemisulfate
- Orciprenaline sulfate USP/EP/BP
- Orciprenaline sulphateQ: What is
Orciprenaline sulphate Q: What is the CAS Number of
Orciprenaline sulphate Q: What is the storage condition of
Orciprenaline sulphate Q: What are the applications of
Orciprenaline sulphate
- Metaproterenol Sulfate (1395500)
- alupent
- METAPROTERENOL SULFATE
- Inhibitor,Beta Receptor,Metaproterenol hemisulfate,inhibit,Orciprenaline hemisulfate,Adrenergic Receptor
- 5874-97-5
- C11H17NO32H2SO4
- 2C11H17NO3H2SO4
- 2C11H17NO3H2O4S
- beta2-adrenoceptor agonist
- Adrenergics
- Agonists
- Neurotransmitters
- Amines
- Aromatics
- Intermediates & Fine Chemicals
- Pharmaceuticals
- 5874-97-5
