Ethyltrimethylsilylacetat
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- CAS-Nr.
- 4071-88-9
- Bezeichnung:
- Ethyltrimethylsilylacetat
- Englisch Name:
- Ethyl (trimethylsilyl)acetate
- Synonyma:
- ETSA;2-trimethylsilylbutanoate;Ethyl(Trimethylsily)Acetate;ETHYL (TRIMETHYLSILYL)ACETATE;ETHYL(2-TRIMETHYLSILYL)ACETATE;ETHYL TRI METHYLSILYLACETATE 99%;Ethyl (trimethylsilyl)acetate,97%;Ethyl acetatethree Methylsilicone;Ethyl (trimethylsilyl)acetate, 98+%;(TRIMETHYLSILYL)ACETIC ACID ETHYL ESTER
- CBNumber:
- CB7271085
- Summenformel:
- C7H16O2Si
- Molgewicht:
- 160.29
- MOL-Datei:
- 4071-88-9.mol
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Ethyltrimethylsilylacetat Eigenschaften
- Siedepunkt:
- 156-159 °C (lit.)
- Dichte
- 0.876 g/mL at 25 °C (lit.)
- Brechungsindex
- n20/D 1.415(lit.)
- Flammpunkt:
- 95 °F
- storage temp.
- Inert atmosphere,Room Temperature
- Löslichkeit
- sol ethereal and chlorinated solvents; reacts with
protic solvents.
- Aggregatzustand
- clear liquid
- Farbe
- Colorless to Almost colorless
- Wichte
- 0.876
- Wasserlöslichkeit
- Decomposition
- Hydrolytic Sensitivity
- 2: reacts with aqueous acid
- Sensitive
- Moisture Sensitive
- BRN
- 1755902
- CAS Datenbank
- 4071-88-9(CAS DataBase Reference)
- NIST chemische Informationen
- Ethyl (trimethylsilyl)acetate(4071-88-9)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| R-Sätze: |
10 |
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| S-Sätze: |
16-24/25 |
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| RIDADR |
UN 3272 3/PG 3 |
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| WGK Germany |
3 |
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| F |
10-21 |
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| TSCA |
Yes |
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| HazardClass |
3 |
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| PackingGroup |
III |
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| HS Code |
29319090 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H226 |
Flüssigkeit und Dampf entzündbar. |
Entzündbare Flüssigkeiten |
Kategorie 3 |
Warnung |
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| Sicherheit |
| P210 |
Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P240 |
Behälter und zu befüllende Anlage erden. |
| P241 |
Explosionsgeschützte [elektrische/Lüftungs-/ Beleuchtungs-/...] Geräte verwenden. |
| P303+P361+P353 |
BEI BERÜHRUNG MIT DER HAUT (oder dem Haar): Alle kontaminierten Kleidungsstücke sofort ausziehen. Haut mit Wasser abwaschen oder duschen. |
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Ethyltrimethylsilylacetat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R10:Entzündlich.
S-Sätze Betriebsanweisung:
S16:Von Zündquellen fernhalten - Nicht rauchen.
Chemische Eigenschaften
Ethyl trimethylsilylacetate is a clear colorless liquid. It is stable to the usual manipulations, and can be stored in glass containers for years without change of physical and spectral properties.
Verwenden
Ethyl trimethylsilylacetate is used in the synthesis of ethyl-2,2-dibromo-2-(trimethylsilyl)acetate and α,β-unsaturated esters. It was also used to silylate the enolizable aldehydes and ketones.
synthetische
ethyl trimethylsilylacetate synthesis: Available by a Reformatsky reaction from ethyl bromoacetate, and by reaction of trimethylsilylmethylmagnesium chloride with ethyl chloroformate. An alternative approach requires the treatment of ethyl acetate with triphenylmethylsodium followed by chlorotrimethylsilane The use of a nitrogen base with ethyl acetate in THF followed by reaction with chlorotrimethylsilane results in a mixture of C- and O-silylation. The use of HMPA as additive in the reaction medium increases the amount of O-silylation to 90%. Similar methods can be used to prepare analogs.
Allgemeine Beschreibung
Reaction of ethyl trimethylsilylacetate (ETSA) with dilute hydrochloric acid, dilute alkali, anhydrous HCl, anhydrous bromine and absolute ethanol has been reported. ETSA undergoes condensation with aromatic aldehydes in the presence of base catalyst to yield β-trimethylsiloxycarboxylates. Lithium ETSA reacts with ketones to yield α,β-unsaturated esters.
läuterung methode
Purify it by distilling ca 10g of reagent through a 15cm, Vigreux column (p 11) and then redistilling it through a 21cm glass helices-packed column [Hauze & Hauser J Am Chem Soc 75 994 1953]. Alternatively, dissolve it in Et2O, wash with H2O, dilute Na2CO3, dry over Na2CO3, evaporate Et2O, and distil it through a column of 15 theoretical plates. [Gold et al. J Am Chem Soc 70 2874 1948, Beilstein 4 IV 3974.]
Ethyltrimethylsilylacetat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Ethyltrimethylsilylacetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 208)Lieferanten
4071-88-9(Ethyltrimethylsilylacetat)Verwandte Suche:
Azidotrimethylsilan
POLY(VINYL ACETATE)
Ethyl-(methylthio)acetat
1,1,1,3,3,3-Hexamethyldisilazan
N-(Trimethylsilyl)acetamid
Ethylacetat
Ethylnitroacetat
Methylacetat
Trimethylsilylacetylen
Natriumacetat
Lithiumbis(trimethylsilyl)amid
Ethyltrifluoracetat
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ylacetat
Ethylphenylacetat
Glatiramer acetate
Vinylacetat
N-(Trimethylsilyl)imidazol
Ethyl-chloracetat
- ETHYL(2-TRIMETHYLSILYL)ACETATE
- ETHYL (TRIMETHYLSILYL)ACETATE
- (TRIMETHYLSILYL)ACETIC ACID ETHYL ESTER
- ETHYL TRI METHYLSILYLACETATE 99%
- Ethyl(Trimethylsily)Acetate
- ETSA~(Trimethylsilyl)acetic acid ethyl ester
- Ethyl (trimethylsilyl)acetate, 98+%
- 2-(Trimethylsilyl)acetic acid ethyl ester
- 2-[Dimethyl(methyl)silyl]acetic acid ethyl ester
- Ethyl (trimethylsilyl)acetate,97%
- (Trimethylsilyl)acetic Acid Ethyl Ester
ETSA
- Ethyl acetatethree Methylsilicone
- Acetic acid, (trimethylsilyl)-, ethyl ester
- ETHYL 2-(TRIMETHYLSILYL)ACETATE, 97%ETHYL 2-(TRIMETHYLSILYL)ACETATE, 97%ETHYL 2-(TRIMETHYLSILYL)ACETATE, 97%
- 2-trimethylsilylbutanoate
- TIANFUCHEM-- 4071-88-9--Ethyl (trimethylsilyl)acetate in stock
- ETSA
- 4071-88-9
- C7H16O2Si
- CH33SiCH2CO2CH2CH3
- CH33SiCH2CO2C2H5
- Carbonyl Compounds
- C6 to C7
- Building Blocks
- Si (Classes of Silicon Compounds)
- Silicon Compounds (for Synthesis)
- Si-(C)4 Compounds
- Organic Building Blocks
- Esters
- Si (Classes of Silicon Compounds)
- Si-(C)4 Compounds
- Silicon Compounds (for Synthesis)
- Synthetic Organic Chemistry
