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1-Tetradecanol Produkt Beschreibung

1-Tetradecanol Struktur
112-72-1
CAS-Nr.
112-72-1
Englisch Name:
1-Tetradecanol
Synonyma:
Epal 14;alfol14;lanettek;loxanolv;myristic;myristyl;Alfol 14;Loxanol V;Lorol C14;dytolr-52
CBNumber:
CB8689436
Summenformel:
C14H30O
Molgewicht:
214.39
MOL-Datei:
112-72-1.mol

1-Tetradecanol Eigenschaften

Schmelzpunkt:
35-39 °C(lit.)
Siedepunkt:
289 °C(lit.)
Dichte
0.823 g/mL at 25 °C(lit.)
Dampfdichte
7.4 (vs air)
Dampfdruck
<1 hPa (20 °C)
Brechungsindex
1.4454
Flammpunkt:
>230 °F
storage temp. 
−20°C
Löslichkeit
water: soluble0.00013g/L at 23°C
Aggregatzustand
Low Melting Solid, Crystalline Powder, Crystals, Flakes, Pellets and/or Chunks
Wichte
0.823
Farbe
White
Wasserlöslichkeit
insoluble
Merck 
14,6335
BRN 
1742652
CAS Datenbank
112-72-1(CAS DataBase Reference)
NIST chemische Informationen
1-Tetradecanol(112-72-1)
EPA chemische Informationen
1-Tetradecanol(112-72-1)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xi
R-Sätze: 38-36
S-Sätze: 24/25-26
RIDADR  UN 3077 9 / PGIII
WGK Germany  -
RTECS-Nr. XB8655000
9
Selbstentzündungstemperatur 489 °F
TSCA  Yes
HS Code  2905 19 00
HazardClass  9
PackingGroup  III
Giftige Stoffe Daten 112-72-1(Hazardous Substances Data)
Toxizität LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rabbit > 2000 mg/kg
Bildanzeige (GHS)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H410 Sehr giftig für Wasserorganismen mit langfristiger Wirkung. Langfristig (chronisch) gewässergefährdend Kategorie 1 Warnung P273, P391, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P273 Freisetzung in die Umwelt vermeiden.
P321 Besondere Behandlung
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
P332+P313 Bei Hautreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
P337+P313 Bei anhaltender Augenreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
P501 Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

1-Tetradecanol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R38:Reizt die Haut.

S-Sätze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

white low melting solid or flakes

Chemische Eigenschaften

Myristyl alcohol occurs as a white crystalline solid with a waxy odor. Also reported as opaque leaflets or crystals from ethanol.

Verwenden

myristyl alcohol is an emollient often used in hand creams, cold creams, and lotions to give them a smooth, velvety feel. Sources indicate it as being mildly comedogenic and potentially irritating.

Verwenden

As emollient for cold creams, etc., also for making the sulfated alcohol whose sodium salt is applicable as a "wetter" in textiles.

Definition

ChEBI: A long-chain fatty alcohol that is tetradecane in which one of the terminal methyl hydrogens is replaced by a hydroxy group

Vorbereitung Methode

Myristyl alcohol is found in spermaceti wax and sperm oil, and may be synthesized by sodium reduction of fatty acid esters or the reduction of fatty acids by lithium aluminum hydride. It can also be formed from acetaldehyde and dimethylamine.

Allgemeine Beschreibung

Colorless thick liquid (heated) with a faint alcohol odor. Solidifies and floats on water.

Air & Water Reaktionen

Insoluble in water.

Reaktivität anzeigen

1-Tetradecanol is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

Health Hazard

Low toxicity. Overexposure causes some central nervous system depression. Prolonged skin contact causes skin irritation.

Pharmazeutische Anwendungen

Myristyl alcohol is used in oral, parenteral, and topical pharmaceutical formulations. It has been evaluated as a penetration enhancer in melatonin transdermal patches in rats.
Myristyl alcohol has also been tested as a bilayer stabilizer in niosome formulations containing ketorolac tromethamine,and zidovudine.Niosomes containing myristyl alcohol showed a considerably slower release rate of ketorolac tromethamine than those containing cholesterol.This was also observed with the zidovudine formulation.

Sicherheit(Safety)

Myristyl alcohol is used in oral parenteral, and topical pharmaceutical formulations. The pure form of myristyl alcohol is mildly toxic by ingestion and may be carcinogenic; experimental tumorigenic data are available.It is also a human skin irritant. In animal studies of the skin permeation enhancement effect of saturated fatty alcohols, myristyl alcohol exhibited a lower effect when compared with decanol, undecanol, or lauryl alcohol but caused greater skin irritation.A study investigating contact sensitization to myristyl alcohol revealed that patch testing of myristyl alcohol 10% petrolatum should not be carried out owing to observed irritant effects; thus the use of a lower concentration of myristyl alcohol for such tests (5% petrolatum) was recommended.Myristyl alcohol has been associated with some reports of contact allergy.(8,9)A moderate-to-severe erythema and moderate edema are seen when 75 mg is applied to human skin intermittently in three doses over 72 hours.
LD50(rabbit, skin): 7.1 g/kg
LD50(rat, oral): 33.0 g/kg

Lager

The bulk material should be stored in a well-closed container in a cool, dry place.

läuterung methode

Crystallise the alcohol from aqueous EtOH. It has also been purified by zone melting. [Beilstein 1 IV 1864.]

Inkompatibilitäten

Myristyl alcohol is combustible when exposed to heat or flame. It can react with oxidizing materials. When heated to decomposition, it emits acrid smoke and irritating fumes.

Regulatory Status

Included in the FDA Inactive Ingredients Database (oral tablet: sustained-release; and topical formulations: cream, lotion, suspension). Included in nonparenteral (topical cream) formulations licensed in the UK.

1-Tetradecanol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


1-Tetradecanol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 203)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21752 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30002 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23976 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8921 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8407 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930501651
breeduan@crovellbio.com CHINA 2314 58

112-72-1()Verwandte Suche:


  • dytolr-52
  • Emery 3334
  • Epal 14
  • Lanette 14
  • Lanette K
  • Lanette Wax KS
  • Lanette Waxd sub 1
  • lanettek
  • lanettewaxks
  • Lorol C14
  • Loxanol V
  • loxanolv
  • myristic
  • Myristryl alcohol
  • myristyl
  • n-Tetradecan-1-ol
  • n-Tetradecanol
  • Alfol 14
  • alfol14
  • Cachalot M-43 NF
  • Dehydag wax 14
  • Dytol R-52
  • n-Tetradecanol-1
  • Philcohol 1400
  • Tetradecan-1-ol
  • Tetradecanol-1
  • MYRISTYL ALCOHOL
  • MYRISTIC ALCOHOL
  • N-TETRADECYL ALCOHOL
  • TETRADECYL ALCOHOL
  • 1-TETRADECANOL
  • 1-HYDROXYTETRADECANE
  • ALCOHOL C14
  • MyristylAlcohol>95%
  • 1-Tetradecanol, 99+%
  • MYRISTYLALCOHOL,REAGENT
  • ALKOHOL C 14 REIN
  • 1-TETRADECANOL 99+% ARGRADE, BOTTLE OF (5)-GM
  • 1-TETRADECANOL, SYNTHESIS GRADE
  • 1-TETRADECANOL (MYRISTYL ALCOHOL)
  • 1-Tetradecanol (Myristyl Alcohol), 99+%
  • C14 Alcohol
  • 1-Tetradecanol (Standard for GC,>99%)
  • MYRISTYL ALCOHOL pure
  • 1-Tetradecanol, 97+%
  • 1-Tetradecanol, synthesis grade DISCONTINUED
  • Myristyl Alcohol (1 g)
  • 1-TETRADECANOL FOR SYNTHESIS 1 KG
  • 1-TETRADECANOL FOR SYNTHESIS 50 KG
  • 1-TETRADECANOL FOR SYNTHESIS 100 G
  • 1-Tetradecanol 97%
  • 1-Tetradecanol Vetec(TM) reagent grade, 97%
  • 1-Tetradecandol
  • Myristyl alcohol Tetradecyl alcohol
  • 112-72-1
  • 112721
  • C14H29OH
  • CH3CH213OH
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